Results 181 to 190 of about 229,255 (286)

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

Alteration in epigenetic profile in subclinical atherosclerosis and in high uric acid. [PDF]

open access: yesSci Rep
Beik-Khormizi M   +5 more
europepmc   +1 more source

Prognostic impact of peak oxygen consumption in heart failure: A systematic review and meta‐analysis

open access: yesESC Heart Failure, EarlyView.
Based on 64 studies, each 1 mL/kg/min increase in VO2peak significantly reduced all‐cause mortality (HR: 0.86, 95% CI 0.82–0.90) and combined outcomes of ventricular assist device, transplant and all‐cause mortality (HR: 0.84, 95% CI 0.79–0.89) in patients with heart failure, though no significant association was observed with cardiovascular mortality (
Konstantinos Prokopidis   +6 more
wiley   +1 more source

Clinical characteristics and outcomes of adults with acute heart failure in a South African teaching hospital

open access: yesESC Heart Failure, EarlyView.
In this study of 406 adults admitted with acute heart failure, the overall in‐hospital mortality rate was 3.4%. Independent predictors of in‐hospital mortality included elevated neutrophil‐lymphocyte ratio, C‐reactive protein, and potassium levels, along with moderate or severe aortic regurgitation and lower diastolic blood pressure.
Umar G. Adamu   +2 more
wiley   +1 more source

End‐organ protective effect of serelaxin in patients hospitalized for heart failure: Results of the biomarker substudy of Relaxin in Acute Heart Failure‐2 (RELAX‐AHF‐2)

open access: yesEuropean Journal of Heart Failure, EarlyView.
End‐organ protective effect of serelaxin in patients with acute heart failure. CV, cardiovascular; HF, heart failure; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide. Abstract Aims Serelaxin is recombinant human relaxin‐2, a hormone responsible for haemodynamic adaptations and organ protection in pregnancy.
Adriaan A. Voors   +12 more
wiley   +1 more source

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