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Seminars in Nephrology, 2005
Hyperuricemia is a common complication in organ transplant recipients, with a higher incidence in kidney and heart recipients. Risk factors for post-transplant hyperuricemia include reduced glomerular filtration rate, diuretic use, cyclosporine therapy, increasing age at transplant, obesity, and metabolic syndrome, as well as the presence of ...
Fernanda Cristina, Mazali +1 more
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Hyperuricemia is a common complication in organ transplant recipients, with a higher incidence in kidney and heart recipients. Risk factors for post-transplant hyperuricemia include reduced glomerular filtration rate, diuretic use, cyclosporine therapy, increasing age at transplant, obesity, and metabolic syndrome, as well as the presence of ...
Fernanda Cristina, Mazali +1 more
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Recent Progress on Uric Acid Detection: A Review
Critical reviews in analytical chemistry, 2020Uric acid (UA), scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. However, an abnormal UA concentration may be connected with many diseases: a higher UA concentration,
Qiangwei Wang, X. Wen, J. Kong
semanticscholar +1 more source
1989
Uric acid is the end product of purine metabolism in humans. In animals other than mammals uric acid undergoes further degradation because of the activity of enzymes such as uricase, allantoinase and allantoinase; in some species the urea that is formed is further hydrolyzed to ammonia and CO2 by the urease of intestinal bacteria (1).
Fuiano G +3 more
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Uric acid is the end product of purine metabolism in humans. In animals other than mammals uric acid undergoes further degradation because of the activity of enzymes such as uricase, allantoinase and allantoinase; in some species the urea that is formed is further hydrolyzed to ammonia and CO2 by the urease of intestinal bacteria (1).
Fuiano G +3 more
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Annals of Internal Medicine, 1979
Excerpt To the editor: The article by Simkin and associates in the July issue (1) discussed a common problem in clinical medicine and provoked much conversation among the physicians here.
B K Jayaswal, C Greenberg
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Excerpt To the editor: The article by Simkin and associates in the July issue (1) discussed a common problem in clinical medicine and provoked much conversation among the physicians here.
B K Jayaswal, C Greenberg
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The American Journal of Medicine, 1968
Urinary tract stones were known in prehistoric times. The oldest stone was unearthed in upper Egypt, dated approximately 4800 B.C. (Shattock, 1905). Stones have been discovered from Egyptian mummies of different dynasties (Miller, 1929; Wesson, 1935; Guthrie, 1946; Sigerist, 1951; Butt, 1956).
Alexander B. Gutman, Ts'ai-Fan Yü
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Urinary tract stones were known in prehistoric times. The oldest stone was unearthed in upper Egypt, dated approximately 4800 B.C. (Shattock, 1905). Stones have been discovered from Egyptian mummies of different dynasties (Miller, 1929; Wesson, 1935; Guthrie, 1946; Sigerist, 1951; Butt, 1956).
Alexander B. Gutman, Ts'ai-Fan Yü
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Current Hypertension Reports, 2006
Hyperuricemia is a frequent finding in diseases in which the clinical manifestations are thought to be secondary to a state of generalized vascular endothelial dysfunction and related to the cardiovascular disease present in conditions associated with the metabolic syndrome, such as hypertension or diabetes.
Michael L. Tuck, Dalila B. Corry
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Hyperuricemia is a frequent finding in diseases in which the clinical manifestations are thought to be secondary to a state of generalized vascular endothelial dysfunction and related to the cardiovascular disease present in conditions associated with the metabolic syndrome, such as hypertension or diabetes.
Michael L. Tuck, Dalila B. Corry
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Urologic Clinics of North America, 2007
Uric acid nephrolithiasis may be the final manifestation of various pathophysiological processes. Recent advances in renal urate transport have elucidated mechanisms by which hyperuricosuria occurs. However, in most uric acid stone formers the primary pathophysiologic defect is an excessively acidic urine pH rather than hyperuricosuria.
Mary Ann Cameron, Khashayar Sakhaee
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Uric acid nephrolithiasis may be the final manifestation of various pathophysiological processes. Recent advances in renal urate transport have elucidated mechanisms by which hyperuricosuria occurs. However, in most uric acid stone formers the primary pathophysiologic defect is an excessively acidic urine pH rather than hyperuricosuria.
Mary Ann Cameron, Khashayar Sakhaee
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The role of uric acid in inflammasome-mediated kidney injury.
Current opinion in nephrology and hypertension, 2020PURPOSE OF REVIEW Uric acid is produced after purine nucleotide degradation, upon xanthine oxidase catalytic action. In the evolutionary process, humans lost uricase, an enzyme that converts uric acid into allantoin, resulting in increased serum uric ...
T. Braga, O. Foresto-Neto, N. Câmara
semanticscholar +1 more source
JAMA: The Journal of the American Medical Association, 1976
GOUTY arthropathy, urate lithiasis, and acute uric acid nephropathy may all complicate the course in a patient who has a malignant disease. All three problems originate from an increased uric acid turnover that occurs in this type of disease.
M C Perry, R D Wagoner, H C Hoagland
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GOUTY arthropathy, urate lithiasis, and acute uric acid nephropathy may all complicate the course in a patient who has a malignant disease. All three problems originate from an increased uric acid turnover that occurs in this type of disease.
M C Perry, R D Wagoner, H C Hoagland
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1989
Uric acid is the end-product of purine nucleotide metabolism in man. The renal handling of urate is a complicated process, resulting in a fractional clearance of 8.2-10.3%. The anhydrous form is thermodynamically the most stable uric acid crystal. Uric acid is a weak acid that ionizes with a Pka at pH 5.75.
A Halabe, Oded Sperling
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Uric acid is the end-product of purine nucleotide metabolism in man. The renal handling of urate is a complicated process, resulting in a fractional clearance of 8.2-10.3%. The anhydrous form is thermodynamically the most stable uric acid crystal. Uric acid is a weak acid that ionizes with a Pka at pH 5.75.
A Halabe, Oded Sperling
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