Development of a multidimensional machine learning framework for predicting post-stroke cognitive impairment: A prospective cohort study. [PDF]
Clinical and Translational Medicine, Volume 15, Issue 12, December 2025.
He A +9 more
europepmc +2 more sources
An Updated Economic Evaluation of HLA-B*58:01 Genotype Testing in Gouty Patients for Preventing Severe Allopurinol Hypersensitivity in Thailand. [PDF]
Objective Human Leukocyte Antigen (HLA), specifically HLA‐B*58:01, testing before allopurinol initiation in patients with gout in Thailand was previously shown to be cost‐effective. However, several drugs are available in the treatment of gout in Thailand, so the updated cost‐effectiveness analysis is warranted.
Dilokthornsakul P +14 more
europepmc +2 more sources
2024 Update of Chinese Guidelines for Diagnosis and Treatment of Hyperuricemia and Gout Part I: Recommendations for General Patients. [PDF]
ABSTRACT Background In 2018, the Chinese Society of Endocrinology developed the “Chinese guideline for diagnosis and treatment of hyperuricemia and gout (2019)”. Over the past 5 years, clinical and experimental research has expanded our knowledge of gout, resulting in novel diagnostic and therapeutic approaches.
Sun M +30 more
europepmc +2 more sources
Hyperuricemia – A narrative review
Gout is an inflammatory disease caused by the accumulation of monosodium urate crystals in joints, cartilage, synovial bursa, tendons, and soft tissues. Gout is highly associated with hyperuricemia.
Chieh Chen
doaj +1 more source
Therapeutic Strategies for the Treatment of Chronic Hyperuricemia: An Evidence-Based Update
This article aims to critically review the evidence on the available therapeutic strategies for the treatment of hyperuricemia. For this reason, several papers were reviewed.
Arrigo F. G. Cicero +3 more
doaj +1 more source
Review of Urate-Lowering Therapeutics: From the Past to the Future
We reviewed all currently available ULT, as well as any medications in development using following databases: United States Food and Drug Administration (FDA), European Medicines Agency (EMA), Japanese Pharmaceutical and Medical Devices Agency (PMDA ...
Christopher Jenkins +7 more
doaj +1 more source
The article provides an overview of new and promising drugs aimed at anti-inflammatory and urate-lowering therapy of gout, both already registered and used in clinical practice, and at the stages of implementation or clinical research and demonstrating ...
A. A. Garanin +2 more
doaj +1 more source
Urate-Lowering Therapy May Prevent the Development of Coronary Artery Disease in Patients With Gout
Substantial evidence has demonstrated a close relationship between hyperuricemia and cardiovascular (CV) diseases, but few studies have explored the possibility of using urate-lowering therapy (ULT) to attenuate the development of CV diseases. To compare
Fu-Shun Yen +11 more
doaj +1 more source
Chronic kidney disease (CKD) is a major global health problem for which there are no curative drug treatments. Hyperuricemia is one of risk factors for CKD.
Hidekatsu Yanai +3 more
doaj +1 more source
Nephrolithiasis against type 2 diabetes mellitus: on the effect of hypoglycemic therapy on lithogenesis [PDF]
Aim. To study the effects of oral hypoglycemic agents that can affect the probability of recurrence of nephrolithiasis. Materials and methods. The article is based on the results of examination and treatment of 315 patients suffering from recurrent ...
S K Yarovoy, E N Kareva, O V Djalilov
doaj +1 more source

