Results 211 to 220 of about 99,858 (332)

Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer Cells

Cell Proliferation, EarlyView.
GLS1‐mediated glutaminolysis supports GSH synthesis in cancer cells. GLS1 KO increases ROS, downregulates GPX4, and upregulates GPX1, making cells more sensitive to ferroptosis. Combining GLS1 or GPX1 inhibitors with a GPX4 inhibitor synergistically suppresses cancer growth.
Changsen Bai, Jialei Hua, Donghua Meng, Yue Xu, Benfu Zhong, Miao Liu, Zhaosong Wang, Wei Zhou, Liming Liu, Hailong Wang, Yang Liu, Lifang Li, Xiuju Chen, Yueguo Li   +13 more
wiley   +1 more source

Alteration of Metabolic Profile in Patients with Narcolepsy Type 1. [PDF]

Metabolites
Hakim MA, Purba W, Sanni A, Bhuiyan MMAA, Talih F, Lanza G, Kobeissy F, Plazzi G, Pizza F, Ferri R, Mechref Y.   +10 more
europepmc   +1 more source

Human Hepatic Uridine Diphosphate Galactose Pyrophosphorylase

, 1969
Hajnalka Ábrahám, R. Rodney Howell
openalex   +1 more source

GLYCOGEN SYNTHESIS FROM URIDINE DIPHOSPHATE GLUCOSE [PDF]

, 1961
David Luck
openalex   +1 more source

Hypertranscription of rDNA Responsible for Nucleolar Remodelling is a Doorman for Acquiring Pluripotency

Cell Proliferation, EarlyView.
Active nucleoli have the capability to release perinuclear heterochromatin, which is a novel event of iPSC reprogramming. ABSTRACT Ribosome biogenesis occurs within the nucleolus, with the initial step being the transcription of ribosomal DNA (rDNA). Although rDNA transcription is limited in somatic cells, it is more active in stem cells. Nevertheless,
Yuchen Sun, Xinglin Hu, Xingwei Huang, Wenyao Zhou, Shubing Lan, Hui Zhang, Guangming Wu, Lei Lei   +7 more
wiley   +1 more source

5,6-Dihydro-5,6-Epoxymultiplolide A, Cytosporone C, and Uridine Production by <i>Diaporthe hongkongensis</i>, an Endophytic Fungus from <i>Minquartia guianensis</i>. [PDF]

Microorganisms
Alexandre ADS, Casas LL, Silva DRD, Nunez CV.   +3 more
europepmc   +1 more source

Enzymatic Transfer of Sulfate from 3‘-Phosphoadenosine 5‘-Phosphosulfate to Uridine Diphosphate N-Acetylgalactosamine 4-Sulfate

, 1967
Tadashi Harada, Satoru Shimizu, Yasuo Nakanishi, Sakaru Suzuki   +3 more
openalex   +1 more source

Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration

Cell Proliferation, EarlyView.
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen, Haijun Zhang, Zhaoheng Wang, Daxue Zhu, Yanhu Li, Yizhi Zhang, Dongxin Wang, Shuwei Chen, Huan Liu, Xuewen Kang   +9 more
wiley   +1 more source

Mass spectrometry imaging reveals spatial metabolic variation and the crucial role of uridine metabolism in liver injury caused by Schistosoma japonicum. [PDF]

PLoS Negl Trop Dis
Xue Q, Zhou X, Wang Y, Liu Y, Li X, Xiong C, Liu X, Huang Y.   +7 more
europepmc   +1 more source

A Uridine Diphosphoacetylmuramyl Hexapeptide from Penicillin-treated Streptococcus faecalis

, 1962
Paul Mandelstam, Richard Loercher, Jack L. Strominger   +2 more
openalex   +1 more source