Results 211 to 220 of about 98,911 (236)
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Feedback onhibition of uridine kinase by cytidine triphosphate and uridine triphosphate
Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects, 1964Abstract Uridine kinase was found to be the rate-limiting step in the anabolism of uridine to its successive nucleotide derivatives. This enzymatic activity was susceptible to feedback inhibition by the pyrimidine nucleoside triphosphate end-products; effective inhibition was exerted by UTP and even more strikingly by CTP.
E.P. Anderson +3 more
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NMR Studies on the Self-Association of Uridine and Uridine Analogues
Chemistry - A European Journal, 1998Association constants for the dimerization of acylated uridine and two analogues, 4-thiouridine and 6-oxadihy- drouridine, have been determined in chloroform solution. At 293 K, self-as- sociation constants K were found to decrease in the order uridine> 6- oxadihydrouridine> 4-thiouridine.
Klaus Weisz +2 more
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Acta Neurologica Scandinavica, 1992
Uridine and other nucleic acids form part of RNA, DNA, coenzymes, second messengers, etc. Uridine uptake in nerve cells is an expression of neuronal RNA synthesis. More knowledge of uridine functions in neurones may give a better understanding of mechanisms underlying dementia, and they could be useful in treating brain tumors.
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Uridine and other nucleic acids form part of RNA, DNA, coenzymes, second messengers, etc. Uridine uptake in nerve cells is an expression of neuronal RNA synthesis. More knowledge of uridine functions in neurones may give a better understanding of mechanisms underlying dementia, and they could be useful in treating brain tumors.
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The Journal of Pediatrics, 1993
To settle the ongoing controversy regarding differential uridine diphosphoglucose (UDPG) and uridine diphosphogalactose (UDPGal) content of erythrocytes, which may be important in evaluating the metabolic abnormality in patients with galactosemia, we derived a combined enzymatic-high-performance liquid chromatography (HPLC) assay.
Shirley Rogers +9 more
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To settle the ongoing controversy regarding differential uridine diphosphoglucose (UDPG) and uridine diphosphogalactose (UDPGal) content of erythrocytes, which may be important in evaluating the metabolic abnormality in patients with galactosemia, we derived a combined enzymatic-high-performance liquid chromatography (HPLC) assay.
Shirley Rogers +9 more
openaire +3 more sources
A dizinc complex for selective fluorescence sensing of uridine and uridine-containing dinucleotides
Chemical Communications, 2007A dizinc complex with a polyamine macrocycle is able to selectively bind and sense uridine (U) as well as the uridine-containing ribodinucleotides U(3'-5')pU and U(3'-5')pA, thanks to an exciplex emission arising from a pi-stacked complex involving the dipyridine unit and Zn(II)-bound uridine moieties.
Barbara Valtancoli +11 more
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Antiarrhythmic Effect of Uridine and Uridine-5’-Monophosphate in Acute Myocardial Ischemia
Bulletin of Experimental Biology and Medicine, 2014Experiments on rats with acute myocardial ischemia accompanied by early postocclusive arrhythmias have shown normalizing, energy-stabilizing, and antiarrhythmic effects of uridine and uridine-5'-monophosphate. The drugs decreased lactate and restored reserves of glycogen and creatine phosphate depleted by ischemia.
E. N. Selina +6 more
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Brain uridine monophosphate: reduced incorporation of uridine during avoidance learning
Brain Research, 1974Abstract Avoidance training produced no detectable changes in the radioactivity incorporated from [5-3H]uridine into total RNA of mouse brain, but decreased the radioactivity in brain uridine monophosphate. The chemical response was largest in the subcortical forebrain, and did not occur in yoked control mice.
Terri Damstra-Entingh +4 more
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Journal of the American Chemical Society, 2014
HnRNP C is a ubiquitous RNA regulatory factor and the principal constituent of the nuclear hnRNP core particle. The protein contains one amino-terminal RNA recognition motif (RRM) known to bind uridine (U)-rich sequences.
Zuzana Cieniková +4 more
semanticscholar +1 more source
HnRNP C is a ubiquitous RNA regulatory factor and the principal constituent of the nuclear hnRNP core particle. The protein contains one amino-terminal RNA recognition motif (RRM) known to bind uridine (U)-rich sequences.
Zuzana Cieniková +4 more
semanticscholar +1 more source
Inhibition of uridine kinase and the salvage of uridine by modified pyrimidine nucleosides.
Molecular Pharmacology, 1985Uridine kinase can play a crucial role in the provision of pyrimidine nucleotides for cellular nucleic acid synthesis, particularly when de novo synthesis is inhibited by chemotherapeutic agents. Therefore, uridine kinase is an attractive target for drug development.
J D, Moyer +6 more
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Measurements of uridine diphosphate glucose and uridine diphosphate galactose — an appraisal
European Journal of Pediatrics, 1995The recent disproof of a major deficiency of uridine diphosphate galactose in galactosemia should not lead investigators to assume either that enzymatic methods are unreliable for uridine sugar assays or that a defect in galactosylation in galactosemia has been excluded.
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