Results 221 to 230 of about 99,858 (332)

Cell type mapping of mild malformations of cortical development with oligodendroglial hyperplasia in epilepsy using single‐nucleus multiomics

open access: yesEpilepsia, EarlyView.
Abstract Objective Mild malformations of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) are brain lesions associated with focal epilepsy and characterized by increased oligodendroglial density, heterotopic neurons, and hypomyelination in the white matter.
Isabella C. Galvão   +10 more
wiley   +1 more source

Status epilepticus in older adults: A critical review

open access: yesEpilepsia, EarlyView.
Abstract Older adults (≥60 years of age) have the highest incidence of status epilepticus (SE) among adults and experience the highest morbidity and mortality. SE incidence increases with age in adulthood. A recent study from Austria estimated an incidence of 89.6/100 000 and 67.6/100 000 person‐years adjusted for age and sex in women and men aged >60 ...
Matthew R. Woodward   +5 more
wiley   +1 more source

Uridine Diphosphate Glucose Dehydrogenase

open access: hybrid, 1968
Pradip Roy‐Burman   +2 more
openalex   +1 more source

Pharmacogenomics of Human Uridine Diphospho‐Glucuronosyltransferases and Clinical Implications

open access: yesClinical pharmacology and therapy, 2014
Chantal Guillemette   +2 more
semanticscholar   +1 more source

Metabolomic and proteomic stratification of equine osteoarthritis

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Equine osteoarthritis (OA) is predominantly diagnosed through clinical examination and radiography, leading to detection only after significant joint pathology. The pathogenesis of OA remains unclear and while many medications modify the disease's inflammatory components, no curative or reversal treatments exist.
James R. Anderson   +5 more
wiley   +1 more source

Pseudouridine: Still mysterious, but never a fake (uridine)!

open access: yesRNA Biology, 2014
Felix Spenkuch, Y. Motorin, M. Helm
semanticscholar   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

open access: yesThe FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický   +22 more
wiley   +1 more source

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