Results 221 to 230 of about 134,815 (339)

Synthesis of 4'-C-α-Aminoethoxy-2'-O-Methyl-5-Methyl- and 5-Propynyl-Uridine Phosphoramidites for Structurally Optimized Antisense Oligonucleotides. [PDF]

Curr Protoc
Mahmoud EM, Ueno Y.
europepmc   +1 more source

Uridine Receptor: Discovery and Its Involvement in Sleep Mechanism [PDF]

, 2001
Toshiyuki Kimura, Ing K. Ho, Ikuo Yamamoto   +2 more
openalex   +1 more source

UGT1A1 and Sacituzumab Govitecan Toxicity: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 63-73, January 2026.
Sacituzumab govitecan (SG), a humanized antibody‐drug conjugate, enables intra‐tumor delivery of SN‐38, the active metabolite of irinotecan, with the aim of increasing efficacy. SN‐38 is predominantly inactivated by the polymorphically expressed uridine diphosphate glucuronosyltransferase 1A1 (UGT1AA) where reduced activity can lead to toxicity.
Cinzia Dello Russo, Innocent Gerald Asiimwe, Sudeep Pushpakom, Carlo Palmieri, Munir Pirmohamed   +4 more
wiley   +1 more source

C‑Nucleosides Stabilize RNA by Reducing Nucleophilicity at 2'-OH. [PDF]

ACS Cent Sci
Banerjee D, Xiao L, Thacker PS, Kundu J, Manoharan M, Kool ET.   +5 more
europepmc   +1 more source

Enzymatic formation of uridine diphosphate N‐acetyl‐D‐mannosaminuronic acid [PDF]

, 1974
Naoshi Ichihara, Nobutoshi Ishimoto, Eiji Ito   +2 more
openalex   +1 more source

THE ENZYMIC INTERCONVERSION OF URIDINE DIPHOSPHOGALACTOSE AND URIDINE DIPHOSPHOGLUCOSE

Journal of Biological Chemistry, 1957
openaire   +2 more sources

Multi‐omics analysis identifies PUS7 as an immune modulator driving NETs‐mediated macrophage polarization in pancreatic cancer

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
PUS7 reshapes the PDAC immune landscape primarily by inducing NETs, which drive macrophage polarization from M1 to M2, fostering immune suppression and tumour progression. The inhibitory effects of S428‐1145 and DNase I on pancreatic cancer are mediated through blocking the PUS7/NETs/M2 macrophage pathway.
Jike Fang, Shiye Ruan, Yajie Wang, Yue Chen, Fuxin Huang, Zhongyan Zhang, Chuanzhao Zhang, Baohua Hou, Shanzhou Huang   +8 more
wiley   +1 more source

Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid pharmacokinetics in glomerulonephritis

, 2010
Melanie S. Joy, Tammy Boyette, Yichun Hu, Jinzhao Wang, Mary K. La, Susan L. Hogan, Paul W. Stewart, Ronald J. Falk, Mary Anne Dooley, Philip C. Smith   +9 more
openalex   +2 more sources

Role of the constant uridine in binding of yeast tRNA^Pheanticodon arm to 30S ribosomes [PDF]

, 1982
Olke C. Uhlenbeck, Peggy T. Lowary, Wayne L. Wittenberg   +2 more
openalex   +1 more source

Regulatory mechanism of O‐linked N‐acetylglucosamine protein modification on autophagy in cancer

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
O‐GlcNAcylation serves as a nutrient and stress sensor that dynamically regulates autophagy at multiple stages in cancer cells. It fine‐tunes autophagy initiation, maturation and fusion by modifying key proteins such as ULK1, ATG4B and SNAP‐29. Context‐dependent O‐GlcNAcylation promotes tumour adaptation and therapy resistance via autophagy remodelling.
Yizhan Li, Ling Gao, Shaoming Li, Jingjing Zheng, Keqian Zhi, Wenhao Ren   +5 more
wiley   +1 more source