Results 211 to 220 of about 75,343 (258)

Biochemistry of uridine in plasma

Clinica Chimica Acta, 2011
Uridine is a pyrimidine nucleoside that plays a crucial role in synthesis of RNA, glycogen, and biomembrane. In humans, uridine is present in plasma in considerably higher quantities than other purine and pyrimidine nucleosides, thus it may be utilized for endogenous pyrimidine synthesis.
Hidenori Koyama, Masafumi Kurajoh, Tetsuo Shoji   +2 more
exaly   +3 more sources

Preparation of uridine diphosphogalactose and uridine diphosphate

Analytical Biochemistry, 1964
Abstract A procedure for the production of UDP-Gal and UDP on a preparative scale has been elaborated using a bacterial mutant which accumulates UDP-Gal in the presence of galactose. This method provides several possibilities for labeling these compounds with radioactive isotopes.
A E, SHEDLOVSKY, H A, BOYE, S, BRENNER
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Phosphorylation of uridine and cytidine by uridine–cytidine kinase

Journal of Biotechnology, 2014
Uridine 5'-monophosphate (5'-UMP) and cytidine 5'-monophosphate (5'-CMP) were biosynthesized by recombinant uridine-cytidine kinase (UCK) and acetate kinase (ACK). The ack and uck genes from Escherichia coli K12 and the uck1, uck2 and ack genes from Lactobacillus bulgaricus ATCC 11842 were cloned and inserted into the plasmid pET-28a.
Yahui Qian, Qingbao Ding, Yanyu Li, Zhi Zou, Bingkun Yan, Ling Ou   +5 more
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Uridyl Transferases and the Formation of Uridine Triphosphate: Enzymic Production of Uridine Triphosphate: Uridine Diphosphoglucose Pyrophosphorolysis

Nature, 1953
Uridyl Transferases and the Formation of Uridine Triphosphate: Enzymic Production of Uridine Triphosphate: Uridine Diphosphoglucose ...
A, MUNCH-PETERSEN, H M, KALCKAR, E, CUTOLO, E E, SMITH   +3 more
openaire   +2 more sources

Effects of uridine on kindling

Epilepsy & Behavior, 2008
The anticonvulsant effect of the nucleoside uridine has been studied for several decades with controversial results. One of its attractive properties is that as a natural endogenous molecule, it lacks the serious side effects of common antiepileptic drugs used today. In the current study, we examined the potential antiepileptogenic effect of uridine in
Qian, Zhao, Tatiana, Shatskikh, Ariane, Marolewski, James R, Rusche, Gregory L, Holmes   +4 more
openaire   +2 more sources

Uridine Kinase: Altered Enzyme with Decreased Affinities for Uridine and CTP

Archives of Biochemistry and Biophysics, 1998
Uridine kinase is the rate-limiting enzyme in the salvage pathway for uridine or cytidine of mammalian cells. Alignment of the uridine kinase sequence with other nucleoside and nucleotide kinases supports a common ancestor for all of these. Three polypeptide segments for the ATP site and three polypeptide segments for the acceptor nucleoside site have ...
P A, Ropp, T W, Traut
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Uridine phosphorylase and uridine kinase activities of the Ehrlich ascites carcinoma

Canadian Journal of Biochemistry, 1969
Uridine phosphorylase and uridine kinase in cell-free extracts of the Ehrlich ascites carcinoma were assayed by a radioactive-tracer technique. Under the assay conditions uridine phosphorylase had an optimum pH of 8.0 and an apparent Km value for uridine of 2.5 × 10−3 M.
Rainnie, D J, Blair, D G
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Feedback onhibition of uridine kinase by cytidine triphosphate and uridine triphosphate

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects, 1964
Abstract Uridine kinase was found to be the rate-limiting step in the anabolism of uridine to its successive nucleotide derivatives. This enzymatic activity was susceptible to feedback inhibition by the pyrimidine nucleoside triphosphate end-products; effective inhibition was exerted by UTP and even more strikingly by CTP.
E P, ANDERSON, R W, BROCKMAN
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Neuronal uridine metabolism

Acta Neurologica Scandinavica, 1992
Uridine and other nucleic acids form part of RNA, DNA, coenzymes, second messengers, etc. Uridine uptake in nerve cells is an expression of neuronal RNA synthesis. More knowledge of uridine functions in neurones may give a better understanding of mechanisms underlying dementia, and they could be useful in treating brain tumors.
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