Results 291 to 300 of about 134,815 (339)

AnticoronavirusActivity of Uridine GlycoconjugatesContaining a 1,2,3-Triazole Moiety

Malgorzata Graul (22017188), Gabriela Brzuska (22017191), Ewa Wisniewska (677136), Monika Dominska (22017194), Petra Strakova (22017197), Daniel Ruzek (7003076), Gabriela Pastuch-Gawolek (22017200), Ewelina Krol (22017203)   +7 more
openalex   +1 more source

Comparative metabolomic and transcriptomic analysis of 2D and 3D mesenchymal stem cell cultures for improved therapeutic applications

British Journal of Pharmacology, Volume 183, Issue 2, Page 379-392, January 2026.
Comparative metabolomic and transcriptomic profiling reveals distinct metabolic shifts and reduced proliferation in 3D MSC spheroids, providing insights to optimise MSC‐based therapies. Abstract Background and Purpose Mesenchymal stem cells (MSCs) are used widely in regenerative medicine due to their multipotency and immunomodulatory properties ...
Manju Shrestha, Yun‐Seo Kil, Yunju Jo, Simmyung Yook, Ki Hyun Kim, Dongryeol Ryu, Joo‐Won Nam, Jee‐Heon Jeong   +7 more
wiley   +1 more source

P2Y14 receptor activation and neutrophil signaling: linking inflammation to systemic pathophysiology. [PDF]

Purinergic Signal
da Silva Ebone R, Doleski PH, Jantsch MH, da Silveira RP, Leal DBR.   +4 more
europepmc   +1 more source

Pre‐Therapeutic UGT1A1 Genotyping in Breast Cancer Patients Receiving Sacituzumab Govitecan to Improve Safety: A Meta‐Analysis and Recommendation

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Pre‐therapeutic UGT1A1 genotyping is increasingly performed in patients receiving irinotecan, as its active metabolite SN‐38 is primarily cleared through UGT1A1‐mediated glucuronidation. Patients with the UGT1A1*28/*28 genotype exhibit reduced UGT1A1 activity, leading to increased SN‐38 exposure and a higher risk of adverse events such as ...
Tessa Goedhart, Henk‐Jan Guchelaar
wiley   +1 more source

Dihydroorotate dehydrogenase inhibition activates STING pathway and pyroptosis to enhance NK cell-dependent tumor immunotherapy. [PDF]

Mol Biomed
Hai Y, Lin R, Liao W, Fu S, Fan R, Ding G, Zhuang J, Zhang B, Liu Y, Song J, Wei G.   +10 more
europepmc   +1 more source

[Determination of uridine-5'-triphosphate, uridine-5'-diphosphate, uridine-5'-monophosphate and uridine by ion exchange chromatography separation and spectrophotometric analysis].

Annali dell'Istituto superiore di sanita, 1969
P, Betto, L, Longinotti
openaire   +1 more source

Structural characterisation of nucleotide sugar short‐chain dehydrogenases/reductases from the thermophilic pseudomurein‐containing methanogen Methanothermobacter thermautotrophicus ΔH

The FEBS Journal, Volume 293, Issue 2, Page 492-513, January 2026.
Nucleotide sugar short‐chain dehydrogenases/reductases (NS‐SDRs) are involved in pseudomurein and capsular polysaccharide formation in methanogenic Archaea. Methanothermobacter thermautotrophicus possesses several NS‐SDRs labelled Mth375, Mth380, Mth373, Mth631 and Mth1789.
Vincenzo Carbone, Linley R. Schofield, Patrick J. B. Edwards, Andrew J. Sutherland‐Smith, Ron S. Ronimus   +4 more
wiley   +1 more source

Adipose tissue releases nucleosides. [PDF]

Am J Physiol Cell Physiol
Zhang J, Le T, Ruiz-Torres V, Cohen M, Paharkova V, Abt E, Alnajjar HS, Tan J, Rashid K, Jones AE, Ball AB, Divakaruni AS, Paszkiewicz RL, Bandaru P, Mack JJ, Ashby JW, Kim J, Li G, Radu CG, Mittelman SD.   +19 more
europepmc   +1 more source

Mechanistic insights into Lin28-dependent oligo-uridylylation of pre-let-7 by TUT4. [PDF]

Nucleic Acids Res
Han X, Yamashita S, Tomita K.
europepmc   +1 more source

Providing a toolbox for genomic engineering of <i>Trichoderma aggressivum</i>. [PDF]

Microbiol Spectr
Schmal M, Kramer LTS, Mach RL, Mach-Aigner AR, Zimmermann C.   +4 more
europepmc   +1 more source