YvcK, a protein required for cell wall integrity and optimal carbon source utilization, binds uridine diphosphate-sugars [PDF]
In Bacillus subtilis, Listeria monocytogenes and in two Mycobacteria, it was previously shown that yvcK is a gene required for normal cell shape, for optimal carbon source utilization and for virulence of pathogenic bacteria.
Elodie Foulquier, Anne Galinier
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Metabolites Profiling of Melanoma Interstitial Fluids Reveals Uridine Diphosphate as Potent Immune Modulator Capable of Limiting Tumor Growth. [PDF]
Tumor interstitial fluid (TIF) surrounds and perfuses tumors and collects ions, metabolites, proteins, and extracellular vesicles secreted by tumor and stromal cells. Specific metabolites, accumulated within the TIF, could induce metabolic alterations of
Vecchio E+24 more
europepmc +2 more sources
Studies on uridine-diphosphate-glucose [PDF]
Blanco y ...
Antonella Paladini, Luis F. Leloir
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Uridine Diphosphate Promotes Rheumatoid Arthritis Through P2Y6 Activation [PDF]
BACKGROUND: Uridine diphosphate (UDP) is an extracellular nucleotide signaling molecule implicated in diverse biological processes via specific activation of pyrimidinergic receptor P2Y, G Protein-Coupled, 6 (P2Y6).
Hongxing Wang+6 more
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Uridine diphosphate N-acetylglucosamine orchestrates the interaction of GlmR with either YvcJ or GlmS in Bacillus subtilis. [PDF]
In bacteria, glucosamine-6-phosphate (GlcN6P) synthase, GlmS, is an enzyme required for the synthesis of Uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a precursor of peptidoglycan.
Foulquier E+4 more
europepmc +2 more sources
The Uridine diphosphate (UDP)-glycosyltransferases (UGTs) superfamily: the role in tumor cell metabolism [PDF]
UDP-glycosyltransferases (UGTs), important enzymes in biotransformation, control the levels and distribution of numerous endogenous signaling molecules and the metabolism of a wide range of endogenous and exogenous chemicals.
Wenyu Liu+4 more
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Glucosylation of (±)-Menthol by Uridine-Diphosphate-Sugar Dependent Glucosyltransferases from Plants [PDF]
Menthol is a cyclic monoterpene alcohol of the essential oils of plants of the genus Mentha, which is in demand by various industries due to its diverse sensorial and physiological properties. However, its poor water solubility and its toxic effect limit
Elisabeth Kurze+8 more
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Uridine Diphosphate Glucose (UDP-G) Activates Oxidative Stress and Respiratory Burst in Isolated Neutrophils [PDF]
The extracellular purinergic agonist uridine diphosphate glucose (UDP-G) activates chemotaxis of human neutrophils (PMN) and the recruitment of PMN at the lung level, via P2Y14 purinergic receptor signaling.
Fabiana Lairion+6 more
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Genomic-Wide Identification and Characterization of the Uridine Diphosphate Glycosyltransferase Family in Eucommia ulmoides Oliver [PDF]
Eucommia ulmoides Oliver is a woody plant with great economic and medicinal value. Its dried bark has a long history of use as a traditional medicinal material in East Asia, which led to many glycosides, such as aucubin, geniposide, hyperoside ...
Dan Ouyang+3 more
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Uridine diphosphate glucose confers oxidative stress tolerance in microalgae [PDF]
Background Microalgae, as major primary producers on Earth, are constantly exposed to oxidative stresses from various natural environments. These oxidative stresses often seriously threaten the productivity and species composition of microalgae. However,
Ruihao Zhang+9 more
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