Results 11 to 20 of about 22,157 (221)

YvcK, a protein required for cell wall integrity and optimal carbon source utilization, binds uridine diphosphate-sugars

Scientific Reports, 2017
In Bacillus subtilis, Listeria monocytogenes and in two Mycobacteria, it was previously shown that yvcK is a gene required for normal cell shape, for optimal carbon source utilization and for virulence of pathogenic bacteria.
Elodie Foulquier, Anne Galinier
doaj   +2 more sources

Chemoenzymatic Synthesis of Uridine Diphosphate-GlcNAc and Uridine Diphosphate-GalNAc Analogs for the Preparation of Unnatural Glycosaminoglycans [PDF]

The Journal of Organic Chemistry, 2012
Eight N-acetylglucosamine-1-phosphate and N-acetylgalactosamine-1-phosphate analogs have been synthesized chemically and were tested for their recognition by the GlmU uridyltransferase enzyme. Among these, only substrates that have an amide linkage to the C-2 nitrogen were transferred by GlmU to afford their corresponding uridine diphosphate(UDP)-sugar
Sayaka, Masuko, Smritilekha, Bera, Dixy E, Green, Michel, Weïwer, Jian, Liu, Paul L, DeAngelis, Robert J, Linhardt   +6 more
openaire   +4 more sources

Thermodynamics of binding of divalent magnesium and manganese to uridine phosphates: implications for diabetes-related hypomagnesaemia and carbohydrate biocatalysis

Chemistry Central Journal, 2008
Background Although the necessity of divalent magnesium and manganese for full activity of sugar nucleotidyltransferases and glycosyltransferases is well known, the role of these metal cations in binding the substrates (uridine 5'-triphosphate, glucose-1-
Pohl Nicola L, Camci-Unal Gulden, Zea Corbin J   +2 more
doaj   +2 more sources

Correction: Uridine diphosphate drives myeloid differentiation and functional reprogramming through dynamic transcriptional network. [PDF]

Front Immunol
Giordano C, Gentile D, Straface E, Gallo R, Cristiani CM, Abatino A, Pastore A, Celano M, Arcucci A, Albano F, Falco G, Veneziano C, Santamaria G, Aversa I, Isdraele Romano L, Palmieri C, Fiume G.   +16 more
europepmc   +2 more sources

Homology Modeling of Human Uridine-5′-diphosphate-glucuronosyltransferase 1A6 Reveals Insights into Factors Influencing Substrate and Cosubstrate Binding

, 2020
The elimination of numerous endogenous compounds and xenobiotics via glucuronidation by uridine-5′-diphosphate glycosyltransferase enzymes (UGTs) is an essential process of the body’s chemical defense system.
Abby C. Collier (6846800), Alexander D. Smith (8602878), Brent D. G. Page (8602881), Michael W. H. Coughtrie (8602884)   +3 more
core   +3 more sources

The Role and Molecular Mechanism of P2Y12 Receptors in the Pathogenesis of Atherosclerotic Cardiovascular Diseases

Applied Sciences, 2021
The P2Y receptor family is a class of G protein-coupled receptors activated primarily by adenosine triphosphate (ATP), adenosine diphosphate (ADP), uridine triphosphate (UTP) and uridine diphosphate (UDP).
Lu Wang, Jinxuan Wang, Jianxiong Xu, Weixi Qin, Yuming Wang, Shisui Luo, Guixue Wang   +6 more
doaj   +1 more source

Uridine diphosphate-glucose 4-epimerase encoding gene galE affects the pathogenicity and carbon metabolism of Ralstonia pseudosolanacearum

浙江大学学报. 农业与生命科学版, 2023
In order to clarify the pathogenic function of uridine diphosphate (UDP)-glucose 4-epimerase encoding gene galE on Ralstonia pseudosolanacearum, the association between galE and the pathogenic-related phenotypes, and the gene deletion effect on ...
ZHANG Hong, LIN Zhijian, ZHU Jindong, LIN Zhaomiao, LI Guoliang, XU Yongqing, LIU Zhonghua, QIU Yongxiang, QIU Sixin   +8 more
doaj   +1 more source

Chemical Oxidation of Uridine Diphosphate-Glucose to Uridine Diphosphate-Glucuronic Acid [PDF]

Nature, 1961
THE importance of uronic acids in carbohydrate metabolism has only recently begun to be elucidated. The metabolism of inositol and ascorbate is known to involve uronic acid intermediates1,2, and nucleotide-bound glucuronic acid has been implicated in hyaluronic acid synthesis3.
B, JACOBSON, E A, DAVIDSON
openaire   +2 more sources

Studies on uridine-diphosphate-glucose [PDF]

Biochemical Journal, 1952
Blanco y ...
Paladini, Alejandro C., Leloir, Luis Federico   +1 more
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URIDINE DIPHOSPHATE ACETYLGLUCOSAMINE

Journal of Biological Chemistry, 1953
Blanco y ...
Cabib, Enrico, Leloir, Luis Federico, Cardini, Carlos E.   +2 more
openaire   +3 more sources