Results 181 to 190 of about 96,444 (318)

Suppressing ABA uridine diphosphate glucosyltransferase (SlUGT75C1) alters fruit ripening and the stress response in tomato

open access: yesThe Plant Journal, 2017
Yufei Sun   +11 more
semanticscholar   +1 more source

Realizing the promise of ‘La Dolce Vita’ via chemical biology: glycan‐motif editing of sLeX for precision cancer therapeutics

open access: yesThe FEBS Journal, Volume 292, Issue 14, Page 3616-3628, July 2025.
Modification of the glycocalyx via ‘glycan editing’ is distinguishable from ‘glycan‐motif editing’. The former broadly remodels the glycocalyx, whereas the latter inhibits expression only of a specific oligosaccharide motif within the glycocalyx by selectively dampening the bioactivity of the key glycosyltransferase(s) programming the biosynthesis of ...
Barbara Richichi, Robert Sackstein
wiley   +1 more source

Y12C mutation disrupts IMPDH cytoophidia and alters cancer metabolism

open access: yesThe FEBS Journal, Volume 292, Issue 14, Page 3676-3695, July 2025.
IMPDH, the rate‐limiting enzyme for de novo GTP synthesis, can form polymers and cytoophidia to enhance activity by reducing GTP inhibition. In this study, a Y12C mutation in IMPDH2 was introduced via ABEmax base‐editing in human cancer cell lines to disrupt IMPDH polymerisation.
Chia‐Chun Chang   +7 more
wiley   +1 more source

Human Hepatic Uridine Diphosphate Galactose Pyrophosphorylase

open access: hybrid, 1969
Hajnalka Ábrahám, R. Rodney Howell
openalex   +1 more source

Abolishing ANAC017‐Mediated Mitochondria Retrograde Signalling Alleviates Ammonium Toxicity in  Arabidopsis thaliana

open access: yesPhysiologia Plantarum, Volume 177, Issue 4, July/August 2025.
ABSTRACT Ammonium (NH4+), an important nitrogen source, often fails to stimulate plant growth as a sole nitrogen source, a phenomenon known as ammonium toxicity syndrome. NH4+ is believed to disrupt cellular redox status by increasing chloroplast reducing capacity and exporting excess reducing equivalents, which trigger retrograde signalling.
Meiyan Ren   +7 more
wiley   +1 more source

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