Results 21 to 30 of about 664,008 (165)

In-silico Leishmania Target Selectivity of Antiparasitic Terpenoids

open access: yesMolecules, 2013
Neglected Tropical Diseases (NTDs), like leishmaniasis, are major causes of mortality in resource-limited countries. The mortality associated with these diseases is largely due to fragile healthcare systems, lack of access to medicines, and resistance by
Ifedayo Victor Ogungbe   +1 more
doaj   +1 more source

Immobilization of the Highly Active UDP-Glucose Pyrophosphorylase From Thermocrispum agreste Provides a Highly Efficient Biocatalyst for the Production of UDP-Glucose

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Biocatalysis that produces economically interesting compounds can be carried out by using free enzymes or microbial cells. However, often the cell metabolism does not allow the overproduction or secretion of activated sugars and thus downstream ...
Antje Kumpf   +12 more
doaj   +1 more source

Transcriptome profiling in Salix matsudana during refilling xylem vessels after embolism

open access: yesBiologia Plantarum, 2019
The objective of this study is to understand the role of bark water uptake in refilling of xylem vessels after embolism in Salix matsudana. Further, we determined expression of genes closely related to xylem embolism repair.
Y.C. Yu, J.X. Liu, Z.Y. Sun
doaj   +1 more source

The Dynamic Influence of Olorofim (F901318) on the Cell Morphology and Organization of Living Cells of Aspergillus fumigatus

open access: yesJournal of Fungi, 2020
The first characterized antifungal in the orotomide class is olorofim. It targets the de novo pyrimidine biosynthesis pathway by inhibiting dihydroorotate dehydrogenase (DHODH).
Saskia du Pré   +7 more
doaj   +1 more source

GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction

open access: yesPlatelets, 2023
GALE gene encodes the uridine diphosphate [UDP]-galactose-4-epimerase, which catalyzes the bidirectional interconversion of UDP-glucose to UDP-galactose, and UDP-N-acetyl-glucosamine to UDP-N-acetyl-galactosamine.
Ana Marín-Quílez   +5 more
doaj   +1 more source

Cloning, Expression and Characterization of UDP-Glucose Dehydrogenases

open access: yesLife, 2021
Uridine diphosphate-glucose dehydrogenase (UGD) is an enzyme that produces uridine diphosphate-glucuronic acid (UDP-GlcA), which is an intermediate in glycosaminoglycans (GAGs) production pathways.
Márcia R. Couto   +2 more
doaj   +1 more source

CryoEM analysis of the essential native UDP-glucose pyrophosphorylase from Aspergillus nidulans reveals key conformations for activity regulation and function

open access: yesmBio, 2023
Invasive aspergillosis is one of the most serious clinical invasive fungal infections, resulting in a high case fatality rate among immunocompromised patients.
Xu Han   +11 more
doaj   +1 more source

Uridine diphosphate glycosyltransferase gene expression profile

open access: yes, 2023
The relative expression levels of uridine diphosphate glycosyltransferase (UGT) gene in the 3rd instar larvae of Galeruca daurica treated with different sublethal concentrations of ...
Yao Tan (16445055)
core   +1 more source

Uridine and its role in metabolic diseases, tumors, and neurodegenerative diseases

open access: yesFrontiers in Physiology
Uridine is a pyrimidine nucleoside found in plasma and cerebrospinal fluid with a concentration higher than the other nucleosides. As a simple metabolite, uridine plays a pivotal role in various biological processes. In addition to nucleic acid synthesis,
Yueyuan Yang   +3 more
doaj   +1 more source

Mulching with plastic film improved the root quality of summer-sown sweet potato (Ipomoea batatas (L). Lam.) in northern China

open access: yesJournal of Integrative Agriculture, 2019
The root quality of sweet potato cultivated during the summer season is poor in northern China; thus, this study was conducted to determine whether root quality could be improved through mulching with plastic film (MPF).
Fu-yun HOU   +5 more
doaj   +1 more source

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