Uridine Diphosphate Glucose (UDP-G) Activates Oxidative Stress and Respiratory Burst in Isolated Neutrophils [PDF]
The extracellular purinergic agonist uridine diphosphate glucose (UDP-G) activates chemotaxis of human neutrophils (PMN) and the recruitment of PMN at the lung level, via P2Y14 purinergic receptor signaling.
Fabiana Lairion +6 more
doaj +2 more sources
Thermodynamics of binding of divalent magnesium and manganese to uridine phosphates: implications for diabetes-related hypomagnesaemia and carbohydrate biocatalysis [PDF]
Background Although the necessity of divalent magnesium and manganese for full activity of sugar nucleotidyltransferases and glycosyltransferases is well known, the role of these metal cations in binding the substrates (uridine 5'-triphosphate, glucose-1-
Pohl Nicola L +2 more
doaj +2 more sources
Uridine diphosphate glucose confers oxidative stress tolerance in microalgae [PDF]
Background Microalgae, as major primary producers on Earth, are constantly exposed to oxidative stresses from various natural environments. These oxidative stresses often seriously threaten the productivity and species composition of microalgae. However,
Ruihao Zhang +9 more
doaj +2 more sources
Studies on uridine-diphosphate-glucose [PDF]
Blanco y ...
Paladini, Alejandro C. +1 more
openaire +5 more sources
UDP-glucose and MRS2905 agonist-bound states of the purinergic P2Y14 receptor [PDF]
P2Y14 receptors respond to uracil-diphosphate-hexose conjugates, yet how this receptor selectively recognizes both uracil-nucleotides and hexose moieties of diverse agonists remains unclear.
Jonathan F. Fay +10 more
doaj +2 more sources
Chemical Oxidation of Uridine Diphosphate-Glucose to Uridine Diphosphate-Glucuronic Acid [PDF]
THE importance of uronic acids in carbohydrate metabolism has only recently begun to be elucidated. The metabolism of inositol and ascorbate is known to involve uronic acid intermediates1,2, and nucleotide-bound glucuronic acid has been implicated in hyaluronic acid synthesis3.
B, JACOBSON, E A, DAVIDSON
openaire +4 more sources
Uridine Diphosphate Glucose: the Coenzyme of the Galactose–Glucose Phosphate Isomerization [PDF]
A PREVIOUS report1 dealt with the enzymatic conversion of galactose-1-phosphate into glucose-1-phosphate and mentioned that a thermostable factor is necessary for the reaction. This factor has now been obtained practically pure, and for reasons given below will be referred to as uridine diphosphate glucose.
Cardini, Carlos E. +3 more
openaire +4 more sources
Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis [PDF]
Collagen glucosyltransferases catalyze collagen glucosylation critical for biology and diseases, yet their structural regulation remains unclear. Here, we report crystal structures of a mimiviral collagen glucosyltransferase in its apo form and in ...
Jeong Seon Kim +12 more
doaj +2 more sources
In order to clarify the pathogenic function of uridine diphosphate (UDP)-glucose 4-epimerase encoding gene galE on Ralstonia pseudosolanacearum, the association between galE and the pathogenic-related phenotypes, and the gene deletion effect on ...
ZHANG Hong +8 more
doaj +1 more source
Multienzyme Platform for the Synthesis of UDP Sugars and Human Milk Oligosaccharides. [PDF]
Engineered Escherichia coli produces six enzymes (UMPK, PPK3, GALK, NAHK, GALU, PPA) that are purified and used in a cell‐free cascade to synthesize UDP‐N‐acetylglucosamine (UDP‐GlcNAc) and UDP‐galactose (UDP‐Gal) from inexpensive substrates. The cascades can be coupled with glycosyltransferases for in situ nucleotide sugar regeneration, enabling ...
Hoang TS +6 more
europepmc +2 more sources

