mBio, 2023 Invasive aspergillosis is one of the most serious clinical invasive fungal infections, resulting in a high case fatality rate among immunocompromised patients.
Xu Han +11 more
doaj +1 more source
Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells [PDF]
, 1990 Undifferentiated and differentiated HL-60 leukemic cells possess nucleotide receptors which functionally couple to phospholipase C via pertussis toxin-sensitive guanine nucleotide-binding proteins (G-proteins).
Seifert, Roland +1 more
core +1 more source
Functional analysis of the Lactococcus lactis galU and galE genes and their impact on sugar nucleotide and exopolysaccharide biosynthesis [PDF]
, 2001 We studied the UDP-glucose pyrophosphorylase (galU) and UDP-galactose epimerase (galE) genes of Lactococcus lactis MG1363 to investigate their involvement in biosynthesis of UDP-glucose and UDP-galactose, which are precursors of glucose- and galactose ...
Boels, I.C. +3 more
core +1 more source
Rhamnose-Containing Compounds: Biosynthesis and Applications
Molecules, 2022 Rhamnose-associated molecules are attracting attention because they are present in bacteria but not mammals, making them potentially useful as antibacterial agents. Additionally, they are also valuable for tumor immunotherapy.
Siqiang Li +6 more
doaj +1 more source
Journal of Integrative Agriculture, 2019 The root quality of sweet potato cultivated during the summer season is poor in northern China; thus, this study was conducted to determine whether root quality could be improved through mulching with plastic film (MPF).
Fu-yun HOU +5 more
doaj +1 more source
Uridine and its role in metabolic diseases, tumors, and neurodegenerative diseases
Frontiers in PhysiologyUridine is a pyrimidine nucleoside found in plasma and cerebrospinal fluid with a concentration higher than the other nucleosides. As a simple metabolite, uridine plays a pivotal role in various biological processes. In addition to nucleic acid synthesis,
Yueyuan Yang +3 more
doaj +1 more source
Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer
BMC Biology, 2019 Altered metabolism and deregulated cellular energetics are now considered a hallmark of all cancers. Glucose, glutamine, fatty acids, and amino acids are the primary drivers of tumor growth and act as substrates for the hexosamine biosynthetic pathway ...
Neha M. Akella +2 more
doaj +1 more source
Identification of a carbohydrate recognition motif of purinergic receptors
eLife, 2023 As a major class of biomolecules, carbohydrates play indispensable roles in various biological processes. However, it remains largely unknown how carbohydrates directly modulate important drug targets, such as G-protein coupled receptors (GPCRs).
Lifen Zhao +7 more
doaj +1 more source
Genome-wide analysis of the UDP-glucose dehydrogenase gene family in Arabidopsis, a key enzyme for matrix polysaccharides in cell walls [PDF]
, 2007 Arabidopsis cell walls contain large amounts of pectins and hemicelluloses, which are predominantly synthesized via the common precursor UDP-glucuronic acid.
Klinghammer, Michaela, Tenhaken, Raimund
core +1 more source
The role of Alg13 N-acetylglucosaminyl transferase in the expression of pathogenic features of Candida albicans. [PDF]
, 2017 Background: The pathogenic potential of Candida albicans depends on adhesion to the host cells mediated by highly glycosylated adhesins, hyphae formation and growth of biofilm. These factors require effective N-glycosylation of proteins.
Janik, Anna +5 more
core +1 more source