Results 81 to 90 of about 12,547 (216)

Study of Bil-Uridine Diphosphate Glucuronyl Transferase (BILUDGPT- 1) Mutation in Neonatal Hyperbilirubinaemia with Glucose-6-Phosphate Dehydrogenase Deficiency. [PDF]

, 2005
Gilbert syndrome is caused by defects in the uridine diphosphate- glucuronosyltransferase 1A1 (UGT1A1) gene. These mutations differ among different populations and many of them have been found to be genetic risk factors for the development of neonatal ...
Mohd Yusoff, Dr Narazah
core  

THE ACTIVITY OF URIDINE DIPHOSPHATE GLUCOSE-GLYCOGEN SYNTHETASE IN SOME EMBRYONIC TISSUES

, 1964
Uridine diphosphate glucose (UDPG)-glycogen synthetase has been studied using chemical and histochemical methods. Activity was demonstrated in whole egg and in homogenates of whole 3-day old chick embryos, in the heart and skeletal muscle from the 5th ...
T. ADESANYA IGE GRILLO, SWETLANA PRICE, PIERO P. FOÁ, GIICHI OKUNO   +3 more
core   +1 more source

Tetramerization is essential for the enzymatic function of the Pseudomonas aeruginosa virulence factor UDP-glucose pyrophosphorylase

mBio
Multidrug-resistant bacteria such as the opportunistic pathogen Pseudomonas aeruginosa, which causes life-threatening infections especially in immunocompromised individuals and cystic fibrosis patients, pose an increasing threat to public health.
Larissa Dirr, Sven Cleeves, Isabel Ramón Roth, Linghui Li, Timm Fiebig, Thomas Ve, Susanne Häussler, Armin Braun, Mark von Itzstein, Jana I. Führing   +9 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Osmolality‐Independent Impact of Sodium on Glycosylation of an Fc‐Fusion Protein and the Hexosamine Biosynthesis Pathway in a Chinese Hamster Ovary Cell Line

Biotechnology Journal, Volume 21, Issue 6, June 2026.
Graphical Abstract and Lay Summary Sodium and potassium supplementation in CHO batch culture elevates intracellular UDP‐HexNAc concentrations through activation of the hexosamine biosynthesis pathway (HBP), independently of osmolality. Increased nucleotide sugar availability enhances Fc‐fusion protein glycosylation and reduces the abundance of low ...
Jason Reiniger, Adrian Pöttner, Lara Rosenberger, Aline Zimmer   +3 more
wiley   +1 more source

Uridine Diphosphate-glucose Dehydrogenase as a Prostate Cancer Biomarker Candidate

, 2014
Prostate cancer is the most common cancer in men. Early detection and diagnosis could potentially lead to a higher cancer survival rate. In this study, the expression of the enzyme uridine diphosphate-glucose dehydrogenase was examined as a possible ...
Cavanagh, Brittin
core  

Metabolic Fingerprinting of Urine Reveals Metabolite Changes in Women With Breast Cancer

Cancer Medicine, Volume 15, Issue 6, June 2026.
This study uses metabolomics to compare urine, plasma and serum metabolite profiles across breast cancer, benign breast disease, symptomatic and healthy controls. Significant metabolic differences—especially in amino acids—were found between BC and other groups, with moderate correlations across biofluids, suggesting potential for non‐invasive BC ...
Nur Aimi Aliah Zainurin, Anuradha U. K. H. Bambarandhage, Michelle Moreno Escalona, Dimitra Ivanova, Tim Gate, Helen Tench, Manfred Beckman, Helen Phillips, Mandana Pennick, Luis A. J. Mur   +9 more
wiley   +1 more source

Uridine diphosphate (UDP) stimulates insulin secretion by activation of P2Y(6) receptors.

, 2008
We examined the transcriptional expression and functional effects of receptors for the extracellular pyrimidines uridine triphosphate (UTP) and uridine diphosphate (UDP), on insulin and glucagon secretion in isolated mouse pancreatic islets and purified ...
Erlinge, David,, Amisten, Stefan,, Salehi, S Albert, Parandeh, Fariborz, Erlinge, David, Abaraviciene, Sandra Meidute, Amisten, Stefan, Salehi, S Albert,, Lund University.   +8 more
core   +1 more source

Disarming the Pathogen's Metabolic Weapon: A Novel Route to Durable Disease Resistance

Modern Agriculture, Volume 4, Issue 1, June 2026.
Two routes to sugar acquisition in pathogenic bacteria and corresponding ‘pathogen‐starvation’ strategies. TAL effectors activate plant SWEET transporters to promote sucrose efflux into the apoplast, which can be blocked by editing SWEET promoter effector‐binding elements to prevent TAL binding. The T3E AvrBs2 converts host UDP‐galactose into xanthosan,
Yixuan Mi, Yuheng Yang
wiley   +1 more source

Abscisic Acid Uridine Diphosphate Glucosyltransferases Play a Crucial Role in Abscisic Acid Homeostasis in Arabidopsis [PDF]

, 2018
The phytohormone abscisic acid (ABA) is crucial for plant growth and adaptive responses to various stress conditions. Plants continuously adjust the ABA level to meet physiological needs, but how ABA homeostasis occurs is not fully understood. This study
Dong, T, Kim, DH, Lee, Y, Hwang, I, Park, Y, Xu, ZY   +5 more
core   +1 more source