Results 81 to 90 of about 664,008 (165)

Indistinguishability and identifiability of kinetic models for the MurC reaction in peptidoglycan biosynthesis [PDF]

, 2009
An important question in Systems Biology is the design of experiments that enable discrimination between two (or more) competing chemical pathway models or biological mechanisms.
Roper, D., D. Bearup, Chappell, M.J., Evans, N.D., N.D. Evans, Evans, Neil D., Hattersley, J.G., Bugg, T., M.J. Chappell, Dowson, Christopher G., D. Roper, Pérez-Velázquez, J., J.G. Hattersley, T. Bugg, Chappell, M. J. (Michael J.), Bearup, Daniel, Bearup, Daniel James, Dowson, C., Hattersley, John G., J. Pérez-Velázquez, Perez-Velazque, J., Roper, David I., Bugg, Tim, C. Dowson   +23 more
core   +1 more source

Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis

Nature Communications
Collagen glucosyltransferases catalyze collagen glucosylation critical for biology and diseases, yet their structural regulation remains unclear. Here, we report crystal structures of a mimiviral collagen glucosyltransferase in its apo form and in ...
Jeong Seon Kim, Zhenhang Chen, Sara Andrea Espinosa Garcia, Christoph Buhlheller, Botao Zhang, Stephen J. Richards, Tingfei Chen, Jingjing Wu, Ronald C. Bruntz, Marisa E. Gilliam, Mitsuo Yamauchi, Bo Liang, Houfu Guo   +12 more
doaj   +1 more source

ANALYSIS OF BILIRUBIN WITH URIDINE-5'-DIPHOSPHATE GLUCURONYLTRANSFERASE.

, 1987
Use of bilirubin uridine 5$\sp\prime$-diphosphate glucuronyltransferase, for the analysis of bilirubin was studied. Microsomal suspensions, as well as the solubilized enzyme, demonstrated capacities for a kinetic assay of albumin: bilirubin (1:2 ...
SHIVJI, ALLY.
core   +1 more source

Uridine prevents the glucose deprivation-induced death of immunostimulated astrocytes via the action of uridine phosphorylase

, 2020
We previously reported that in immunostimulated astrocytes, glucose deprivation induced cell death via the loss of ATP, reduced glutathione, and mitochondrial transmembrane potential.
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Effect of uridine 5'-diphosphate on cryogenic brain edema in rabbits.

, 1989
This study was undertaken to examine the effect of uridine 5'-diphosphate, administered intravenously or intraperitoneally, on cold injury-induced brain edema in rabbits.
S Yoshida, M D Bailey, S S Moore, K Kitamura, J F Alksne, J M Seelig   +5 more
core   +1 more source

Effect of moxibustion at “Zusanli” (ST36) on metabolites of gastric tissue in rats with chronic atrophic gastritis based on metabonomics

针刺研究, 2019
Objective To observe the effect of moxibustion at"Zusanli"(ST36)on metabolites of gastric tissue in chronic atrophic gastritis(CAG)rats,so as to explore the correlation between Yangming Meridian and stomach based on metabolomics.Methods Fifty-six SD rats
LIU Xia, SHE Chang, ZHONG Huan, LIU Tao, CAO Jia-nan, ZHANG Chi, LIU Mi, CHANG Xiao-rong   +7 more
doaj   +2 more sources

CRISPR/Cas9-Based Functional Characterization of SfUGT50A15 Reveals Its Roles in the Resistance of Spodoptera frugiperda to Chlorantraniliprole, Emamectin Benzoate, and Benzoxazinoids

Insects
UDP-glycosyltransferases (UGTs) are a diverse superfamily of enzymes. Insects utilize uridine diphosphate-glucose (UDP-glucose) as a glycosyl donor for glycosylation in vivo, involved in the glycosylation of lipophilic endosymbionts and xenobiotics ...
Zhan Shi, Mei Luo, Jinxi Yuan, Bin Gao, Minghuan Yang, Guirong Wang   +5 more
doaj   +1 more source

Uridine diphosphate-glucose/P2Y14R axis is a nonchemokine pathway that selectively promotes eosinophil accumulation. [PDF]

J Clin Invest, 2021
Foster PS, Tay HL, Hogan SP.
europepmc   +1 more source

Coupling of uridine-5'-diphosphate (UDP) formation and nicotinamide adenine dinucleotide (NAD+) reduction for cytochemical localization of glycosyltransferases.

, 1983
A technique applicable to the cytochemical localization of glycosyltransferases through a series of coupled enzyme reactions is described. Uridine-5'-diphosphate (UDP) formed by glycosyltransferases is first phosphorylated to uridine-5'-triphosphate ...
G R Matyas, D J Morré
core   +1 more source

Targeted LC-MS profiling reveals dysregulated glycolytic flux and TCA cycle stalling in POAG plasma

Scientific Reports
Glaucoma is the leading cause of irreversible blindness. Primary open-angle glaucoma (POAG) is the most common form globally and has been linked to mitochondrial dysfunction and energy deficiency.
Yizhen Tang, Xuanqi Zhang, Xiaoxiao Chen, Jiayong Li, Minyue Xie, Qianru Wu, Yinghan Zhang, Chi-wai Do, Xinghuai Sun   +8 more
doaj   +1 more source