Results 101 to 110 of about 664,008 (165)

Targeting UGCG sensitizes AML cells to venetoclax through RAB32-mediated endoplasmic reticulum-mitochondria communication

Cell Reports
Summary: Uridine diphosphate (UDP)-glucose ceramide glucosyltransferase (UGCG) is an enzyme that glycosylates ceramide and blunts its pro-apoptotic activity in cancer cells. Targeting UGCG sensitizes solid cancer cells to chemotherapy.
Xiaofan Sun, Yue Li, Danqi Pan, Caiping Wu, Weihao Xiao, Ganlu Feng, Nianhui Yang, Yizhen Li, Wei Xiong, Min Dai, Zhirou Zhang, Lei Hua, Liye Zhong, Guopan Yu, Suxia Geng, Chengxin Deng, Chengwei Luo, Ping Wu, Xin Du, Juan Du, Hui Zeng   +20 more
doaj   +1 more source

Enhancing Glycosylation of Flavonoids by Engineering the Uridine Diphosphate Glucose Supply in Escherichia coli

Glycosylation can enhance the solubility and stability of flavonoids. The main limitation of the glycosylation process is low intracellular uridine diphosphate glucose (UDPG) availability.
Jingwen Zhou (591817), Shike Liu (6287315), Weizhu Zeng (6523394), Zhijie Qin (9941580), Dong Li (212687)   +4 more
core   +1 more source

Characterization of PmHS2 glycosyltransferases for the controlled synthesis of heparosan : a precursor of heparin and heparan sulfate [PDF]

, 2011
Heparin (Hep), a highly sulfated and complex glycosaminoglycan polysaccharides, is worldwide used as an anticoagulant compound to prevent blood clotting during surgery.
Chavaroche, A.A.E.
core  

Purification of uridine diphosphate glucuronyltransferase

, 1983
Detoxification of compounds occurs in two phases. In phase I, a functional group on the toxicant is made available for subsequent Phase II reactions. In phase II, the functional groups are conjugated to a compound that will increase the solubility of the
Duffaud, Guy Daniel
core  

Uridine diphosphate-glucose 6-dehydrogenase-mediated glucuronidation and its emerging role in gut-liver immune regulation. [PDF]

World J Gastrointest Oncol
Yang YQ, Li N, Liu S, Yu YW.
europepmc   +1 more source

Chromosome-scale genome assembly, carbohydrate metabolism transcriptome atlas, and candidate genes for polysaccharide accumulation in <i>Asparagus cochinchinensis</i>. [PDF]

Front Plant Sci
Zhao J, Yan F, Chen A, Liu D, Wu J, Wang L, Liu S, Chen Y, Zhang W, Tang L, Li Q, Xu Z, Yu M, Lyu X.   +13 more
europepmc   +1 more source

The Role of Pyrophosphate in the Origin of Life: An Energy-Based Hypothesis. [PDF]

Biology (Basel)
Villa-Bellosta R.
europepmc   +1 more source

Osmolality-Independent Impact of Sodium on Glycosylation of an Fc-Fusion Protein and the Hexosamine Biosynthesis Pathway in a Chinese Hamster Ovary Cell Line. [PDF]

Biotechnol J
Reiniger J, Pöttner A, Rosenberger L, Zimmer A.   +3 more
europepmc   +1 more source

In vitro action of uridine diphosphate glucose (UDPG) on phrenic diaphragm preparations

, 1979
The action of uridine-5'-diphosphoglucose (UDPG) on the contractile response of the phrenic diaphragm preparation from guinea pig was investigated.
DOSSENA, MAURIZIA, TANZI, FRANCO, PASTORIS, ORNELLA, RAIMONDO S   +3 more
core  

Efficient, complete biosynthesis of isoflavonoid calycosin-7-glucoside by metabolically engineered yeast cell factories. [PDF]

Front Bioeng Biotechnol
Zhang W, Xu M, Wang L, Qiao X, Yang S, Liu Y, Liu Q, Lu X.   +7 more
europepmc   +1 more source