Results 11 to 20 of about 126,321 (267)

Alpha-synuclein amyloids catalyze the degradation of ATP and other nucleotides [PDF]

Scientific Reports
Intracellular accumulation of alpha-synuclein amyloids is a main pathological hallmark in a subgroup of human neurodegenerative diseases called synucleinopathies.
Claudio Castillo-Cáceres, Esteban Nova, Rodrigo Diaz-Espinoza   +2 more
doaj   +2 more sources

Symptomatic improvement in an acute, non-traumatic spine pain model with a combination of uridine triphosphate, cytidine monophosphate, and hydroxocobalamin

Conference on Privacy, Security and Trust, 2014
Rationale: In a previously published trial on spinal acute non-traumatic pain, peripheral neuro- regenerative combination of UTP, CMP and hydroxocobalamin presented unexpected analgesicproperties.
Marco Antonio Mibielli, Carlos Pereira Nunes, Ari Boulanger Scussel, Mendel Suchmacher Neto, Lisa Oliveira, Mauro Geller   +5 more
openalex   +3 more sources

Enzymatic synthesis and reverse transcription of RNAs incorporating 2′-O-carbamoyl uridine triphosphate

Chemical Communications, 2016
Enzymatic synthesis and the reverse transcription of RNAs containing 2'-O-carbamoyl uridine were evaluated. A mild acidic deprotection procedure allowed the synthesis of 2'-O-carbamoyl uridine triphosphate (UcmTP).
Y. MASAKI, Hyugo Ito, Yuki Oda, Kazufumi Yamazaki, Nobuhiro Tago, Kentaro Ohno, Nozomi Ishii, Hirosuke Tsunoda, Takashi Kanamori, Akihiro Ohkubo, Mitsuo Sekine, Kohji Seio   +11 more
openalex   +3 more sources

A case of folinic acid, fluorouracil and oxaliplatin (FOLFOX) chemotherapy regimen associated neurotoxicity and review of literature [PDF]

BMC Neurology
FOLFOX (folinic acid, 5-fluorouracil, and oxaliplatin) chemotherapy regimen is a widely used chemotherapy agent for the management of gastrointestinal malignancies. FOLFOX has been linked to various toxicities including peripheral neurotoxicity.
Juhi Srivastava, Esha Kataria DO, Sanjeev Sivakumar, Naresh Mullaguri   +3 more
doaj   +2 more sources

Dual Signaling Pathways of Arterial Constriction by Extracellular Uridine 5′-Triphosphate in the Rat

Journal of Pharmacological Sciences, 2011
We investigated actions of uridine 5′-triphosphate (UTP) in rat aorta, cerebral and mesenteric arteries, and their single myocytes. UTP (≥10 μM) elicited an inward-rectifying current strongly reminiscent of activation of P2X1 receptor, and a similar ...
Megumi Sugihara, Hiromitsu Morita, Miho Matsuda, Hisanori Umebayashi, Shunichi Kajioka, Shinichi Ito, Motohiro Nishida, Ryosuke Inoue, Toshiko Futatsuki, Jun Yamazaki, Yasuo Mori, Ryuji Inoue, Yushi Ito, Kihachiro Abe, Masato Hirata   +14 more
doaj   +3 more sources

A Distinctive Metabolomics Pattern Associated with the Administration of Combined Sacubitril/Valsartan to Healthy Subjects: A Kinetic Approach [PDF]

Pharmaceuticals
Background/Objective: Sacubitril/Valsartan are a combination drug approved for heart failure treatment, known to enhance natriuretic peptide activity and inhibit the renin–angiotensin–aldosterone system (RAAS).
Randh AlAhmari, Hana M. A. Fakhoury, Reem AlMalki, Hatouf H. Sukkarieh, Lina Dahabiyeh, Tawfiq Arafat, Anas M. Abdel Rahman   +6 more
doaj   +2 more sources

Reaction of Guanosine Triphosphate and Uridine Triphosphate with Actomyosin Gel [PDF]

Acta Chemica Scandinavica, 1954
Rolf Bergkvist, Adam Deutsch, G. Hevesy, Paavo Pääkkönen, Oiva Järvelä   +4 more
openaire   +2 more sources

ENZYMATIC AMINATION OF URIDINE TRIPHOSPHATE TO CYTIDINE TRIPHOSPHATE

Journal of Biological Chemistry, 1956
Irving Lieberman
openaire   +3 more sources

The Isolation of Uridine-5'-Triphosphate from Muscle. [PDF]

Acta Chemica Scandinavica, 1954
Rolf Bergkvist, Adam Deutsch, Chr. Klixbüll Jørgensen, Nils Andreas Sörensen   +3 more
openaire   +2 more sources

Lowback Pain Management with a Combination of Uridine Triphosphate, Cytidine Monophosphate, and Hydroxocobalamin: A Systematic Review and Meta-Analysis. [PDF]

Rev Bras Ortop (Sao Paulo)
Mibielli MAN, Suchmacher M, Geller M, Mezitis SGE, Nunes CP, Sintoveter A.   +5 more
europepmc   +4 more sources