Results 1 to 10 of about 19,779,561 (150)

Comparison of laparoscopic and robot-assisted partial nephrectomy for intermediate/high-complexity endophytic renal tumors (R.E.N.A.L.-NS ≥ 7): a propensity score-matched retrospective study

open access: yesBMC Cancer
Purpose To compare operative, functional, and oncological outcomes between laparoscopic partial nephrectomy (LPN) and robot-assisted partial nephrectomy (RAPN) for intermediate/high-complexity (R.E.N.A.L.
Luyao Chen   +12 more
doaj   +1 more source

Transfixed jejunum lesion due to percutaneous nephrolithotomy

open access: yesUrology Case Reports, 2021
Percutaneous access for treatment of renal pathologies is a minimally invasive modality, although it can present complications. Small bowel lesions are rare but correct diagnosis and management are essential to prevent major complications.
Victor S.S. Fanni   +5 more
doaj   +1 more source

Irrigation fluid absorption induces metabolic and oxidative stress dysregulation activating NLRP3 and NF-κB pathways to drive hippocampal inflammatory responses

open access: yesFrontiers in Pharmacology
BackgroundIrrigation fluid absorption during endoscopic procedures can lead to serious complications, but its effects on hippocampal function remain poorly understood.
Qihui Zheng   +12 more
doaj   +1 more source

Unraveling the role of gut microbiota by fecal microbiota transplantation in rat model of kidney stone disease

open access: yesScientific Reports
Emerging research on the microbiome highlights the significant role of gut health in the development of kidney stones, indicating that an imbalance in gut bacteria or dysbiosis can influence the formation of stones by altering oxalate metabolism and ...
Sittiphong Hunthai   +8 more
doaj   +1 more source

Association Between BAK1 Gene rs210138 Polymorphisms and Testicular Germ Cell Tumors: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Endocrinology, 2020
Background: Several studies including some genome-wide association studies (GWAS) had shown that BAK1 gene rs210138 polymorphisms might be associated with testicular germ cell tumors (TGCT).
Jiaxuan Qin   +11 more
doaj   +1 more source

SLAMF8 Participates in Acute Renal Transplant Rejection via TLR4 Pathway on Pro-Inflammatory Macrophages

open access: yesFrontiers in Immunology, 2022
BackgroundAcute rejection (AR) in kidney transplantation is an established risk factor that reduces the survival rate of allografts. Despite standard immunosuppression, molecules with regulatory control in the immune pathway of AR can be used as ...
Lisha Teng   +38 more
doaj   +1 more source

USP7 promotes chemotherapy resistance and DNA damage response through stabilizing and deubiquitinating KDM4A in bladder cancer

open access: yesCell Death and Disease
Bladder cancer is a common malignancy, and the insensitivity of advanced bladder cancer to cisplatin poses an imminent challenge to treatment. Our study aims to identify novel targets that mediate cisplatin responsiveness in bladder cancer.
Hailang Yang   +14 more
doaj   +1 more source

Relationship between C-reactive protein-triglyceride-glucose index and lower urinary tract symptoms due to benign prostatic hyperplasia in Chinese older adults: a nationwide longitudinal cohort study

open access: yesShiyong laonian yixue
[Objective] To investigate the association between C-reactive protein-triglyceride-glucose index (CTI) and the risk of developing lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH/LUTS).
XU Xueyuan   +3 more
doaj   +1 more source

Evodiamine induces ferroptosis in prostate cancer cells by inhibiting TRIM26-mediated stabilization of GPX4

open access: yesChinese Medicine
Background Prostate cancer is a major global health challenge, characterized by high morbidity and mortality rates. Traditional treatment options, including androgen deprivation therapy and chemotherapy, often lead to drug resistance.
Lanlan Li   +7 more
doaj   +1 more source

Development and preclinical evaluation of a novel FGFR3-targeted antibody-drug conjugate in bladder cancer

open access: yesAsian Journal of Pharmaceutical Sciences
Given the critical shortage of antibody-drug conjugates (ADCs) for bladder cancer (BCa), we developed a novel FGFR3-targeted ADC, LZU-WZLYFG001, composed of a humanized anti-FGFR3 IgG1 monoclonal antibody, a cleavable GGFG linker, and the payload DXD ...
Guangrui Fan   +16 more
doaj   +1 more source

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