Results 131 to 140 of about 99,653 (320)

Distinct ligand binding sites in integrin alpha3beta1 regulate matrix adhesion and cell-cell contact. [PDF]

, 2003
The integrin alpha3beta1 mediates cellular adhesion to the matrix ligand laminin-5. A second integrin ligand, the urokinase receptor (uPAR), associates with alpha3beta1 via a surface loop within the alpha3 beta-propeller (residues 242-246) but outside ...
Chapman, Harold A, Ching, Tsui-Ting, Kreidberg, Jordan A, Kugler, Matthias C, Tom, Clifford C, Wei, Ying, Zhang, Feng   +6 more
core  

The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain. [PDF]

, 2016
GPIHBP1 is a glycolipid-anchored membrane protein of capillary endothelial cells that binds lipoprotein lipase (LPL) within the interstitial space and shuttles it to the capillary lumen.
Beigneux, Anne P, Bensadouen, André, Fong, Loren G, Gårdsvoll, Henrik, Jørgensen, Thomas Jd, Kristensen, Kristian Kølby, Larsson, Mikael, Mysling, Simon, Ploug, Michael, Young, Stephen G   +9 more
core   +2 more sources

Kinetic Redox Shotgun Proteomics Reveals Specific Lipopolysaccharide Effects on Intestinal Epithelial Cells, Mitigated by a Mn Superoxide Dismutase Mimic

Angewandte Chemie, Volume 137, Issue 19, May 5, 2025.
Proteomics and redoxomics are efficient to quantify the effects of bacterial lipopolysaccharide in intestinal epithelial cells (HT29) at the proteome and at the Cys‐redoxome levels. Oxidative stress is the initial trigger of LPS leading to inflammation.
Martha Zoumpoulaki, Giovanni Chiappetta, Jean Bouvet, Namita‐Raju John, Gabrielle Schanne, Pauline Gehan, Samuel Diebolt, Shakir Shakir, Elodie Quévrain, Emilie Mathieu, Sylvie Demignot, Philippe Seksik, Nicolas Delsuc, Joelle Vinh, Clotilde Policar   +14 more
wiley   +2 more sources

Acute modified Blalock-Taussing shunt obstruction successfully treated with urokinase and heparin [PDF]

, 2005
Acute modified Blalock-Tuassig shunt obstruction due to thrombosis may be lifethreatening. We report non-invasive relief of shunt obstruction with thrombolysis and heparinisation, a potentially life-saving intervention that is applicable in all ...
Grech, Victor E., Mizzi, Joseph
core   +1 more source

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase

Journal of Cell Biology, 1985
The secretion of plasminogen activators has been implicated in the controlled extracellular proteolysis that accompanies cell migration and tissue remodeling.
J. Vassalli, D. Baccino, D. Belin
semanticscholar   +1 more source

Circadian misalignment disrupts biomarkers of cardiovascular disease risk and promotes a hypercoagulable state

European Journal of Neuroscience, Volume 60, Issue 7, Page 5450-5466, October 2024.
We studied the impact of circadian misalignment on 238 plasma proteins linked to cardiovascular physiology. We identified 42 proteins with altered abundance, five proteins regulated by the circadian clock, and changes in many proteins in the coagulation pathway.
Andrew W. McHill, Edward L. Melanson, Kenneth P. Wright Jr, Christopher M. Depner   +3 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

, 1967
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1024/thumbnail ...

core   +1 more source

Effects of natto extract on endothelial injury in a rat model [PDF]

, 2010
Vascular endothelial damage has been found to be associated with thrombus formation, which is considered to be a risk factor for cardiovascular disease. A diet of natto leads to a low prevalence of cardiovascular disease. The aim of the present study was
Chang, Chin-Hsien, Chang, Yen-Lin, Chen, Kuo-Ti, Chiu, Ya-Huang, Hsieh, Ching-Liang, Kuo, Yi-Wen, Lee, Tsong-Hai, Wang, Chao-Hung, Wu, Chang-Jer   +8 more
core   +1 more source

Postoperative TIPS Reaction in a Patient With Portal Vein Dysfunction

Portal Hypertension &Cirrhosis, EarlyView.
Qihao Du, Jiaming Lan, Ke Xu, Meng Niu
wiley   +1 more source

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur, Christopher Dowson, Susan M. Bissett, Rachel van de Merwe, John J. Taylor, Philip M. Preshaw, Katrin M. Jaedicke   +6 more
wiley   +1 more source