Identification of a Novel Small RNA Encoded in the Mouse Urokinase Receptor uPAR Gene (Plaur) and Its Molecular Target Mef2d [PDF]
Frontiers in Molecular Neuroscience, 2022 Urokinase receptor (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored receptor of urokinase (uPA), which is involved in brain development, nerve regeneration, wound healing and tissue remodeling. We have recently shown that Plaur, which encodes uPAR,
Karina D. Rysenkova +21 more
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Modulation of Cellular Function by the Urokinase Receptor Signalling: A Mechanistic View [PDF]
Frontiers in Cell and Developmental Biology, 2022 Urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycosyl-phosphatidyl-inositol anchored (GPI) membrane protein. The uPAR primary ligand is the serine protease urokinase (uPA), converting plasminogen into plasmin, a broad spectrum ...
Daniela Alfano +2 more
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TLR4 Response to LPS Is Reinforced by Urokinase Receptor [PDF]
Frontiers in Immunology, 2020 GPI-anchored uPAR is the receptor for the extracellular serine protease urokinase-type plasminogen activator (uPA). Though uPAR role in inflammatory processes is documented, underlying mechanisms are not fully understood.
Yulia Kiyan +8 more
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Data on the inhibition of cell proliferation and invasion by the D2A-Ala peptide derived from the urokinase receptor [PDF]
Data in Brief, 2019 The data presented in this article are connected to our research article entitled “D2A-Ala peptide derived from the urokinase receptor exerts anti-tumoural effects in vitro and in vivo” (Furlan et al., 2018).
Federico Furlan +8 more
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Soluble urokinase receptor is a kidney-specific vasoconstrictorResearch in context [PDF]
EBioMedicineSummary: Background: Soluble urokinase plasminogen activator receptor (suPAR) is an innate immune system-derived risk factor for acute and chronic kidney diseases.
Sebastian Buhl Rasmussen +11 more
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Influence of Endoplasmic Reticulum Stress on Urokinase Plasminogen Activation [PDF]
BiomoleculesThe urokinase plasminogen activator or urokinase is a highly specific extracellular protease involved in numerous physiological and pathological processes.
Diana Culej Bošnjak +4 more
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AP1 Transcription Factor in the Regulation of the Urokinase Plasminogen Activation System [PDF]
BiomoleculesUrokinase plasminogen activation system regulates the activation of plasminogen to produce the ubiquitous extracellular protease plasmin. It is involved in different physiological and pathophysiological processes, which involve tissue reorganization ...
Petra Korać +2 more
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Soluble Urokinase Receptor and the Kidney Response in Diabetes Mellitus [PDF]
Journal of Diabetes Research, 2017 Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD) worldwide. DN typically manifests by glomerular hyperfiltration and microalbuminuria; then, the disease progresses to impaired glomerular filtration rate, which leads to ...
Ranadheer R. Dande +3 more
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Soluble Urokinase Receptor and Acute Kidney Injury [PDF]
New England Journal of Medicine, 2020 David E Leaf +2 more
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Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas [PDF]
Scientific Reports, 2017 The development of metastases is a multistep process that requires the activation of physiological and biochemical processes that govern migration, invasion and entry of metastatic cells into blood vessels.
Maria Vincenza Carriero +13 more
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