Results 41 to 50 of about 78,313 (276)

Thrombectomy combined with indwelling-catheter thrombolysis is more effective than pure thrombectomy for the treatment of lower extremity deep venous thrombosis

Open Medicine, 2017
This study was a retrospective analysis of the efficacy of thrombectomy plus local catheter-directed thrombolysis (CDT) for the treatment of lower extremity deep venous thrombosis (LDVT).
Wang Wenli, Wu Yanfang, Fang Tao, Xu Dunyuan   +3 more
doaj   +1 more source

Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]

, 2003
Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R., Braungart, E., Degitz, K., Douwes, K., Flaig, M. J., Magdolen, V., Probst, C., Sander, C. A., Schuh, T., Wosikowski, K.   +9 more
core   +1 more source

Diabetes decreases patency of tunneled catheters in hemodialysis patients after first effective thrombolysis with urokinase

Renal Failure, 2018
Introduction: Fibrinolysis is one of the methods extending the use of vascular access in patients with tunneled venous catheters thrombosis. The aim of this study was to assess one-year maintenance of tunneled catheters patency after first effective ...
Dominika Wójtowicz, Dominika Cholewa, Anna M. Faba, Beata Domańska, Joanna Kokoszka, Konrad Kopacz, Rafał Ficek, Tomasz Irzyniec, Sylwia E. Rotkegel, Jerzy Chudek   +9 more
doaj   +1 more source

Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisy

Respirology Case Reports, 2020
Medical thoracoscopy, also called “local anesthetic thoracoscopy” and “pleuroscopy,” is a minimally invasive single‐port endoscopic technique that provides direct visualization of the pleural surfaces and channels to conduct diagnostic and therapeutic ...
Satoshi Terashita, Hiroaki Kawachi, Tomoko Tajiri, Susumu Noguchi, Tatsuyoshi Ikeue, Takakazu Sugita   +5 more
doaj   +1 more source

Construction of ultrasound-responsive urokinase precise controlled-release nanoliposome applied for thrombolysis

Frontiers in Bioengineering and Biotechnology, 2022
Urokinase is widely used in the dissolution of an acute pulmonary embolism due to its high biocatalytic effect. However, how to precisely regulate its dose, avoid the side effects of hemolysis or ineffective thrombolysis caused by too high or too low a ...
Yongliang Fan, Yongliang Fan, Li Liu, Fang Li, Hang Zhou, Yizhou Ye, Chunping Yuan, Hongli Shan, Wangfu Zang, Yu Luo, Sijing Yan   +10 more
doaj   +1 more source

Hippocampal Viral-Mediated Urokinase Plasminogen Activator (uPA) Overexpression Mitigates Stress-Induced Anxiety and Depression in Rats by Increasing Brain-Derived Neurotrophic Factor (BDNF) Levels

Biomolecules
Emerging evidence suggests the serine protease, urokinase plasminogen activator (uPA), may play an important role in the modulation of mood and cognitive functions. Also, preliminary evidence indicates that uPA modulates BDNF activity that is known to be
Amine Bahi, Jean-Luc Dreyer
doaj   +1 more source

Intrapleural injection of urokinase in the treatment of acute Haemophilus influenza empyema in children: A case report and literature review

Frontiers in Pediatrics, 2022
ObjectiveThe purpose of this study is to analyze the clinical data of a child with acute empyema caused by Haemophilus influenzae, and to investigate the diagnosis and treatment of this disease through literature review to improve the clinical ...
Lin Yang, YaFei Zhu, GuangSheng Wu
doaj   +1 more source

Minimally Invasive Technique for Spontaneous Intraparenchymal Hemorrhage

Indian Journal of Neurosurgery
Objective The aim of this study was to introduce a cost-effective and less invasive method for the evacuation of intraparenchymal hemorrhage (IPH).
Himanshu Raval, Kalpesh Shah, Mona Bhatt
doaj   +1 more source

Intrapleural Instillation of Sodium Bicarbonate versus Urokinase in Management of Complicated Pleural Effusion: A Comparative Cohort Study

International Journal of General Medicine, 2022
Niveen E Zayed,1 Karim El Fakharany,2 Mohammed Mehriz Naguib Abozaid1 1Department of Chest Disease, Faculty of Medicine, Zagazig University, Zagazig City, Egypt; 2Department of Cardiothoracic Surgery, Faculty of Medicine, Zagazig University, Zagazig City,
Zayed NE, El Fakharany K, Mehriz Naguib Abozaid M   +2 more
doaj  

MicroRNA 449a can Attenuate Protective Effect of Urokinase Against Pulmonary Embolism

Frontiers in Pharmacology, 2022
Acute pulmonary embolism (APE) is a disabling diseases with high incidence rate and mortality rate. Although with high specificity, D-Dimer lacks specificity to assess APE, hence additional diagnostic and prognostic biomarkers are necessary.
Ran Zhu, Wei-yi Qi, Ting-wei Liu, Fan Liu   +3 more
doaj   +1 more source