Results 21 to 30 of about 32,805 (191)

Fibrinolysis versus thoracoscopy: Comparison of results in empyema management in the child

open access: yesAnnals of Thoracic Medicine, 2022
OBJECTIVE: The objective of this study is to compare the outcome of treatment with drainage and urokinase (UK) versus thoracoscopy (TS) in pleural empyema secondary to complicated pneumonia.
Maria Rosa Ibarra Rodriguez   +5 more
doaj   +1 more source

Role of multidomain structure of urokinase in regulation of growth and remodeling of vessels [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2013
Urokinase type plasminogen activator, or urokinase (uPA), is a multifunctional protein which plays special regulatory role in the vascular wall and can actuate the proteolytic and signal cascades.
V. A. Tkachuk   +3 more
doaj   +1 more source

Thrombectomy combined with indwelling-catheter thrombolysis is more effective than pure thrombectomy for the treatment of lower extremity deep venous thrombosis

open access: yesOpen Medicine, 2017
This study was a retrospective analysis of the efficacy of thrombectomy plus local catheter-directed thrombolysis (CDT) for the treatment of lower extremity deep venous thrombosis (LDVT).
Wang Wenli   +3 more
doaj   +1 more source

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

open access: yesAdvanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett   +15 more
wiley   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

open access: yesAdvanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin   +3 more
wiley   +1 more source

Construction of ultrasound-responsive urokinase precise controlled-release nanoliposome applied for thrombolysis

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Urokinase is widely used in the dissolution of an acute pulmonary embolism due to its high biocatalytic effect. However, how to precisely regulate its dose, avoid the side effects of hemolysis or ineffective thrombolysis caused by too high or too low a ...
Yongliang Fan   +10 more
doaj   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

open access: yesAdvanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang   +10 more
wiley   +1 more source

Ultrasound-Guided Urokinase in the Remedy of Spontaneous Vaginal Hematoma After Vaginal Delivery: A Case Report

open access: yesInternational Journal of Women's Health, 2023
Jin Shang,1 Juan Li,2 Qing Bai,2 Yongmei Wang,2 Hongjian Chen,1 Shunxu Li2 1Department of Ultrasound, The Third People’s Hospital of Yunnan, Kunming, People’s Republic of China; 2Department of Obstetrics, The Third People’s Hospital of Yunnan, Kunming ...
Shang J   +5 more
doaj  

Urokinase-based lock solutions for catheter salvage: A case of an upcoming kidney transplant recipient

open access: yesOpen Medicine, 2023
Catheter-related bloodstream infection (CRBSI) is a significant complication among patients on haemodialysis (HD) who are dependent on a central venous catheter (CVC) for an extended period. Catheter removal as first-line treatment can induce accelerated
Xia Cong   +6 more
doaj   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda   +4 more
wiley   +1 more source

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