Results 41 to 50 of about 32,805 (191)

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Role of Urokinase in Delayed Presentation of Deep Vein Thrombosis: Single Center Experience

Indian Journal of Vascular and Endovascular Surgery
Background: Deep vein thrombosis (DVT) is a common and potentially devastating condition that can lead to permanent disability with significant morbidity and mortality.
Kesha Shah, Apurva Shah, Sourabh Mittal, Sunil Dixit, Anil Sharma   +4 more
doaj   +1 more source

A Case of Venous Tissue Dissection During Transcatheter MitraClip Surgery

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The MitraClip system has been widely used to treat mitral regurgitation. The complications associated with MitraClip surgery typically include clip detachment and mitral valve injury. However, cases of venous tissue dissection during surgery are relatively rare.
Shumin Ouyang, Yongqiao Zhou, Yongzhao Yao, Guangzhu Liang, Minqi Liao, Suxia Guo   +5 more
wiley   +1 more source

Intrapleural injection of urokinase in the treatment of acute Haemophilus influenza empyema in children: A case report and literature review

Frontiers in Pediatrics, 2022
ObjectiveThe purpose of this study is to analyze the clinical data of a child with acute empyema caused by Haemophilus influenzae, and to investigate the diagnosis and treatment of this disease through literature review to improve the clinical ...
Lin Yang, YaFei Zhu, GuangSheng Wu
doaj   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Intra-arterial thrombolysis for acute ischemic stroke: Our institutional experience

Indian Journal of Neurosurgery, 2012
Introduction The standard treatment for acute ischemic stroke is intravenous (IV) rtPA for patients who can reach the hospital within 3 to 4.5 h. There are case reports, where IA thrombolysis has helped patients in case an IV thrombolysis has failed.
R.V. Narayana, Rajesh Pati, Sibasankar Dalai   +2 more
doaj   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

Epilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara, Erwin A. van Vliet, Alessia Romagnolo, Kevin Staley, Kyle P. Lillis, Chris Dulla, David C. Henshall, Katja Kobow   +7 more
wiley   +1 more source

Predicting Mortality in African Americans With Type 2 Diabetes Mellitus: Soluble Urokinase Plasminogen Activator Receptor, Coronary Artery Calcium, and High‐Sensitivity C‐Reactive Protein

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundType 2 diabetes mellitus is a major risk factor for cardiovascular disease; however, outcomes in individual patients vary. Soluble urokinase plasminogen activator receptor (suPAR) is a bone marrow–derived signaling molecule associated with ...
Salim S. Hayek, Jasmin Divers, Mohamad Raad, Jianzhao Xu, Donald W. Bowden, Melissa Tracy, Jochen Reiser, Barry I. Freedman   +7 more
doaj   +1 more source

Fibrinolytics: from the thrombolysis to the processes of blood vessels growth and remodeling, neurogenesis, carcinogenesis and fibrosis [PDF]

Терапевтический архив, 2019
One of the most outstanding scientific achievements in the thrombolysis is the development and administration of fibrinolysin - the first Soviet drug that lyses blood clots.
V A Tkachuk, Ye V Parfyonova, O S Plekhanova, V V Stepanova, M Yu Menshikov, E V Semina, R Sh Bibilashvili, E I Chazov   +7 more
doaj   +1 more source