Results 101 to 110 of about 489,677 (387)
Advanced Science, EarlyView.Prevention and treatment of diabetic kidney disease (DKD) have become a major global public health challenge. This study shed new light on the underlying pathogenic mechanisms of podocyte injury in DKD and highlights the therapeutic potential of mitigating podocyte injury through inhibition of the RIPK3/NF‐κB p65‐mediated inflammatory response as a ...
Lu'an Li +10 more
wiley +1 more source
Advanced Science, EarlyView.Cu7S4 nanozymes, exhibiting peroxidase‐like, catalase‐like, and GSH‐depletion activities, are synthesized through defect engineering. These nanozymes demonstrate rapid inactivation of Gram‐negative bacteria, including Escherichia coli and Pseudomonas aeruginosa. In a mouse skin wound model infected with P. aeruginosa, the nanozyme showcases exceptional
Xueya Li +15 more
wiley +1 more source
Guidelines for reporting of statistics for clinical research in urology
BJU International, 2019 In an effort to improve the quality of statistics in the clinical urology literature, statisticians at European Urology, The Journal of Urology, Urology and BJU International came together to develop a set of guidelines to address common errors of ...
M. Assel +15 more
semanticscholar +1 more source
Advanced Science, EarlyView.In hepatocellular carcinoma (HCC), the m6A‐modified circRAPGEF1 destabilizes ASS1 mRNA via competitive binding to IGF2BP3, driving aspartate metabolic reprogramming in liver cancer stem cells (LCSCs). This cascade enhances stemness properties and reduces sorafenib sensitivity in LCSCs, thereby identifying circRAPGEF1 as a promising therapeutic target ...
Juanyi Shi +13 more
wiley +1 more source
An analysis of the use of acute hospital resources, by the residents of Bexley and Greenwich [PDF]
, 1997 An analysis was conducted of the use of acute hospital resources by the residents of the two Boroughs of Bexley and Greenwich. The data related to hospital episode statistics for 1996/97.
Marchant, M., Plant, Paul
core
Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction
Advanced Science, EarlyView.Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu +14 more
wiley +1 more source
Advanced Science, EarlyView.Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li +16 more
wiley +1 more source
Enhanced NIR-II Nanoparticle Probe for PSMA-Targeted Molecular Imaging and Prostate Cancer Diagnosis
International Journal of NanomedicineZhongji Jiang,1,2 Jin Zhang,3 Jiali Jin,3 Xun Zhang,4 Gaohaer Kadeerhan,5 Hong Guo,3 Dongwen Wang2,6 1Department of Biology, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, People’s Republic of China ...
Jiang Z +6 more
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