Results 101 to 110 of about 361,421 (310)

Urology HEIRS: A Feasibility and Acceptability Study for Video-Based Research on Physician-Family Communication in Pediatric Urology Visits [PDF]

Purpose: Patient- and family-centered communication is essential to health care equity. However, less is known about how urologists implement evidence-based communication and dynamics involved in caring for diverse pediatric patients and caregivers.
Rink, R, Dangle, PP, Lester, JN, Koehlinger, J, Dangle, Pankaj P., Whittam, B, Kaefer, Martin, Meldrum, Kirstan, Mattei, Jennifer K., Rink, Richard, Koehlinger, Jeremy, Meldrum, K, Williamson, FA, Szymanski, KM, Kaefer, M, Misseri, R, Roth, Joshua, Lester, Jessica Nina, Mattei, JK, Misseri, Rosalia, Whittam, Benjamin, Williamson, Francesca A., Szymanski, Konrad M., Roth, J   +23 more
core   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Elevated Visceral Adiposity Index is Associated with Reproductive Endocrine Characteristics, and Adverse Pregnancy Outcomes in Chinese Women with Polycystic Ovary Syndrome

International Journal of Women's Health
Baichao Shi,1 Jiaxing Feng,2 Fengjuan Lu,1 Muxin Guan,1 Jiannan Yu,1 Zhuwei Gao,1 Yu Wang,2 Jing Cong,2 Hongli Ma,2 Conghui Han,3 Wen Yang,4 Xiaoke Wu,2,5 Jingshu Gao5 1Graduate School, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang ...
Shi B, Feng J, Lu F, Guan M, Yu J, Gao Z, Wang Y, Cong J, Ma H, Han C, Yang W, Wu X, Gao J   +12 more
doaj  

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Preserve the tract and turn it inside out (PATIO) robotic vesicovaginal fistula repair - a novel approach

Urology Video Journal
Vesicovaginal Fistulas (VVFs) are abnormal communications between the bladder and the vagina, commonly caused by obstetric or gynecologic injuryDifferent surgical approaches have been executed for VVF repair: Transvaginal, transabdominal, and ...
Alexandra Kata, Kyle Michelson, Lucas R Wiegand   +2 more
doaj   +1 more source

Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

Advanced Science, EarlyView.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang, Guoruiyu Lyu, Wenlong Wan, Dongfeng Yuan, Jiabo Li, Yongqi Wang, Baokang Wang, Zhilong Ma, Yuanyuan Yang, Yang Xun, Xiao Yu   +10 more
wiley   +1 more source

Renal IGFBP6 Interacts With THBS1 to Drive Renal Cellular Senescence and Fibrosis

Advanced Science, EarlyView.
ABSTRACT Epithelial dedifferentiation and myofibroblast activation are critical drivers of chronic kidney disease (CKD) progression. Elevated levels of IGFBP6 have been linked to decreased renal function in CKD patients, but its precise role and underlying mechanisms remain unclear.
Ju‐tao Yu, Chang‐geng Xu, Xiao‐wei Hu, Run‐run Shan, Jia‐nan Wang, Xiang‐yu Li, Yu‐qing Wang, Yu‐hang Dong, Shen‐Zhuo‐Fan Huang, Shuai Sun, Tian Zhao, Ya‐Xin Ru, Xiao‐yu Shen, Rui Hou, Jian‐min You, Fei Zhang, Chao Li, Jie Wei, Chao Hou, Zhi‐juan Wang, Dan‐feng Zhang, Juan Jin, Jia‐gen Wen, Yu‐jie Liu, Ming‐ming Liu, Xiao‐ming Meng, Wei Wang   +26 more
wiley   +1 more source

RNA Binding Motif Protein 15 (RBM15): Structure, Function and Its Research Progress in Tumors

International Journal of General Medicine
Xiangyu Long,* Bintao Hu,* Shiqing Zhu, Yue Wu, Tao Wang Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China*These authors ...
Long X, Hu B, Zhu S, Wu Y, Wang T
doaj  

Lower Urinary Tract Symptoms in Men Living with Human Immunodeficiency Virus: A Case-control Study

Journal of Urological Surgery
Objective: Human immunodeficiency virus (HIV)/acquired immune deficiency syndrome constitutes a global pandemic affecting populations worldwide. There’s a gap in data regarding lower urinary tract symptoms (LUTS) among men living with HIV (MLWH) during ...
Ersin Köseoğlu, Ömer Acar, Umut Can Karaarslan, İbrahim Can Aykanat, Süda Tekin, Tufan Tarcan   +5 more
doaj   +1 more source

EFFICACY OF ALFUZOSIN VERSUS CONTROL GROUP IN UPPER URETERIC STONE EXPULSION IN ADULT POPULATION OF LAHORE, PAKISTAN

Gomal Journal of Medical Sciences, 2022
Background: Urinary stone disease is one of the commonest urological diseases worldwide. The objective of this study was to compare the efficacy of alfuzosin versus control group in upper ureteric stone expulsion in adult population of district Lahore ...
Fawad Humayun, Ghulam Mujtaba, Muhammad Seerwan, Ghazi Khan, Naseem Javed, Muhammad Adnan   +5 more
doaj