Results 71 to 80 of about 496,608 (402)

Management of urachal cancer in pregnancy: A systematic review

open access: yesBJUI Compass, 2022
Urachal cancer is a rare non‐urothelial malignancy that involves the urachus, often occurring at the junction of the urachal ligament and the bladder dome. It accounts for less than 1% of all bladder tumours.
Kenneth K. Y. Chew   +3 more
doaj   +1 more source

CircPVT1 Promotes Lung Metastasis and Tumor Progression in Renal Cell Carcinoma by Encoding the cP104aa Peptide and Targeting EIF4A3

open access: yesAdvanced Science, EarlyView.
This study reveals that circPVT1 promotes the renal cell carcinoma lung metastasis and tumor progression through encoding the cP104aa peptide and directly binds with EIF4A3, which jointly regulates the target gene c‐MYC. Abstract Circular RNA (circRNA) plays a pivotal role in the pathogenesis of renal cell carcinoma (RCC).
Houliang Zhang   +10 more
wiley   +1 more source

Free ureteral replacement in rats: regeneration of ureteral wall components in the acellular matrix graft. [PDF]

open access: yes, 1997
ObjectivesTo evaluate ureteral replacement by a free homologous graft of acellular matrix in a rat model.MethodsIn 30 male Sprague-Dawley rats, a 0.3 to 0.8-cm midsegment of the left ureter was resected and replaced with an acellular matrix graft of ...
Dahiya, R   +5 more
core   +1 more source

m6A‐Modified circRAPGEF1 Interaction with IGF2BP3 Promotes Hepatocellular Carcinoma Progression via Reprogramming Aspartate Metabolism

open access: yesAdvanced Science, EarlyView.
In hepatocellular carcinoma (HCC), the m6A‐modified circRAPGEF1 destabilizes ASS1 mRNA via competitive binding to IGF2BP3, driving aspartate metabolic reprogramming in liver cancer stem cells (LCSCs). This cascade enhances stemness properties and reduces sorafenib sensitivity in LCSCs, thereby identifying circRAPGEF1 as a promising therapeutic target ...
Juanyi Shi   +13 more
wiley   +1 more source

Staged Urethroplasty in a Patient with Urethral Stricture Following Female to Male Transgender Surgery

open access: yesJournal of Urological Surgery
Complications of urethral reconstruction are common in patients who have undergone female to male transgender surgery. Patients may develop urethral strictures and fistulas, which lead to repeated surgery.
Ozan Bozkurt   +9 more
doaj   +1 more source

Genomic biomarkers in prostate cancer. [PDF]

open access: yes, 2018
Prostate cancer is the most common non-cutaneous cancer among men in the United States. In the last decade there has been a rapid expansion in the field of biomarker assays for diagnosis, prognosis, and treatment prediction in prostate cancer.
Cooperberg, Matthew R   +3 more
core  

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

open access: yesAdvanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu   +14 more
wiley   +1 more source

Frailty and elderly in urology: Is there an impact on post-operative complications? [PDF]

open access: yes, 2017
INTRODUCTION: Frailty used as predictive tool is still not carried out in daily practice, although many studies confirm the great clinical importance of the frailty syndrome in surgical outcomes.
Barbieri, Lisa   +4 more
core   +1 more source

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

open access: yesAdvanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang   +12 more
wiley   +1 more source

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