Results 71 to 80 of about 360,869 (356)

MCUB Inhibits PRKN‐Dependent Mitophagic Degradation of PD‐L1 to Promote Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, the overexpression of MCUB not only reduces mitochondrial calcium influx but also facilitates its binding to PRKN at Arg51, both mechanisms contribute to the impairment of PRKN‐mediated mitophagy. Consequently, the degradation of PD‐L1 is suppressed, leading to its stable expression on the tumor cell surface.
Yuan Huang, Chen Chen, Mingqiang Su, Dongqing Li, Jinge Zhang, Kuangye Long, Wenbin Nie, Shu Wei, Wei Chen, Haiyong Chen, Zhangfeng Zhong, Lina Hou, Wanlong Tan, Fei Li   +13 more
wiley   +1 more source

Enhanced NIR-II Nanoparticle Probe for PSMA-Targeted Molecular Imaging and Prostate Cancer Diagnosis

International Journal of Nanomedicine
Zhongji Jiang,1,2 Jin Zhang,3 Jiali Jin,3 Xun Zhang,4 Gaohaer Kadeerhan,5 Hong Guo,3 Dongwen Wang2,6 1Department of Biology, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, People’s Republic of China ...
Jiang Z, Zhang J, Jin J, Zhang X, Kadeerhan G, Guo H, Wang D   +6 more
doaj  

PD02-06 HEALTHCARE-ASSOCIATED INFECTIONS BY MULTIDRUG-RESISTANT BACTERIA IN A TERTIARY UROLOGY DEPARTMENT [PDF]

, 2016
Vera Regina Beltrão Marques, F. Rolo, Edgar Tavares-da-Silva, Alexandra Torres, Arnaldo Figueiredo, Alfredo Mota   +5 more
openalex   +1 more source

Under‐Urine‐Adhered Supramolecular Hydrogel with Linearly Sustained Quercetin Release Facilitates Hemorrhagic Cystitis Healing via Inflammation Regulation

Advanced Science, EarlyView.
A supramolecular gelatin‐based hydrogel adhesive was engineered for hemorrhagic cystitis management. It provides robust wet‐tissue adhesion, rapid hemostasis, sustained quercetin release, effectively restoring the bladder barrier via anti‐inflammatory and antioxidant actions.
Xu Cao, Hua Zhang, Yang Luo, Yaoqi Chen, Jie Yao, Renhao Ni, Tong Zhu, Yudong Yao, Jun Chen, Baolin Guo, Kerong Wu   +10 more
wiley   +1 more source

Oncological cases and complications in Urology

, 2021
Massimiliano Bernabei, Antonia Di Domenico, Gil Falcão, Charalampos Fragkoulis, Andrea Benelli, Martina Beverini, Luís Campos Pinheiro, Cabrita Carneiro, Nicolò Fabbri, Ioannis Glykas, Salvatore Greco, Carlo Introini, Konstantinos Ntoumas, Georgios Papadopoulos, Mariangela Rutigliani, Panagiotis Velissarios Stamatakos, João Vasco Barreira   +16 more
openalex   +2 more sources

Monocyte‐Differentiation‐Activated Fluorescent “Scout” Probe for Precise in Vivo Detection of Vulnerable Plaque

Advanced Science, EarlyView.
An innovative monocyte‐differentiation‐activated fluorescent “scout” probe (MDAF) leverages the inherent chemotaxis of monocytes toward vulnerable plaques (VAP) to enable efficient targeted delivery while achieving spatiotemporally controllable activation of its AIE fluorescent signals with the dynamic differentiation of monocytes, providing an ...
Zechuan Li, Jiankai Dong, Zhengkun Liu, Chaoke Zhang, Jisen Li, Ying Tao, Ding Yang, Yansong Liu, Haoting Chen, Lu Liu, Jingsen Ji, Feng Cao, Dan Ding, Qian Liu, Chenxing Fu, Weisheng Guo   +15 more
wiley   +1 more source

Summary Paper on the 2023 European Association of Urology Guidelines on the Management of Non-neurogenic Male Lower Urinary Tract Symptoms.

European Urology, 2023
S. Gravas, M. Gacci, C. Gratzke, T. Herrmann, M. Karavitakis, I. Kyriazis, S. Malde, C. Mamoulakis, M. Rieken, V. Sakalis, Natasha Schouten, M. Speakman, K. Tikkinen, J. Cornu   +13 more
semanticscholar   +1 more source

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source

RNA Binding Motif Protein 15 (RBM15): Structure, Function and Its Research Progress in Tumors

International Journal of General Medicine
Xiangyu Long,* Bintao Hu,* Shiqing Zhu, Yue Wu, Tao Wang Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China*These authors ...
Long X, Hu B, Zhu S, Wu Y, Wang T
doaj  

A pH‐Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury

Advanced Science, EarlyView.
A biomimetic nanoplatform (CeAst@MK) is engineered for precise therapy of acute kidney injury by integrating cerium‐based antioxidation, natural flavonoid astragalin, and macrophage membrane camouflage. Featuring kidney‐targeted and pH‐responsive release, CeAst@MK scavenges ROS, suppresses inflammation, and restores renal function via modulation of ...
Shichao Zhang, Yuhan Xie, Longchao Zhang, Yuanjiong Qi, Quan Liao, Chenglong Xu, Shushuai Yang, Haiwen Zhou, Qidan Tan, Shiyong Qi   +9 more
wiley   +1 more source