Results 71 to 80 of about 361,421 (310)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Antibiotic Prophylaxis in Urology Departments, 2005-2010 [PDF]

open access: yes, 2013
Background: Antibiotic prophylaxis (AP) is an important measure in preventing health care-associated urinary tract infections (HAUTIs). Despite regional variations in the bacterial spectrum and antibiotic susceptibility patterns, guideline ...
van Oostrum, Edgar   +6 more
core   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

open access: yesAdvanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma   +13 more
wiley   +1 more source

Research Needs for Effective Transition in Lifelong Care of Congenital Genitourinary Conditions: A Workshop Sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases. [PDF]

open access: yes, 2017
Over the last 5 decades, health-care advances have yielded quantum improvements in the life expectancy of individuals with congenital genitourinary conditions (CGCs), leading to a crisis of care.
Scal, Peter   +21 more
core   +1 more source

Continuum Mechanics Modeling of Flexible Spring Joints in Surgical Robots

open access: yesAdvanced Robotics Research, EarlyView.
A new mechanical model of a tendon‐actuated helical extension spring joint in surgical robots is built using Cosserat rod theory. The model can implicitly handle the unknown contacts between adjacent coils and numerically predict spring shapes from straight to significantly bent under actuation forces.
Botian Sun   +3 more
wiley   +1 more source

Changes in urologic research from a new perspective: Text mining analysis of publication topics [PDF]

open access: yesInvestigative and Clinical Urology
Purpose: This study aimed to explore the trends in research keywords and topics in the field of urology based on text mining over the recent decades. The investigation looked into changes in frequent subject keywords and the trends in prevailing research
Soohyung Joo   +4 more
doaj   +1 more source

Hybrid Continuum Robot Designs and Architectures for Healthcare Applications

open access: yesAdvanced Robotics Research, EarlyView.
Hybrid continuum robots represent an emerging class of flexible manipulators that blend materials, structures, and actuation concepts from the established fields of soft and continuum robotics. This review introduces an accessible framework to distinguish key hybridization approaches, surveys current designs aimed at complex clinical applications, and ...
Burak Ozdemir   +4 more
wiley   +1 more source

Urofluxômetro computadorizado com detector de esforço abdominal [PDF]

open access: yes, 1998
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.
Monteiro, Ciro José Egoavil
core  

Top cited articles in urology from Turkey [PDF]

open access: yes, 2017
Objective: Citation is the name given for a scientific publication in order to be used as a reference by another publication. In this study, we reviewed the most frequently cited publications in urology from Turkey. Material and methods: On March 7-14,
Mustafa Yuksel   +5 more
core   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

open access: yesAdvanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang   +11 more
wiley   +1 more source

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