Results 21 to 30 of about 1,483 (209)

Comparison of Trifecta and Pentafecta Outcomes across 3 Surgical Modalities of Partial Nephrectomy (PN) – Open, Lap, and Robotic [PDF]

Journal of Kidney Cancer and VHL
Renal cell carcinoma (RCC) is the most common solid tumor in the kidney (90%), accounting for about 3% of all cancers in adults. Partial nephrectomy (PN) is the surgical procedure primarily used for the treatment of localized kidney tumors. Two commonly
Hiranya Deka, N. Mallikarjunarao Medam, Ginil Kumar P., Vishnu P, Manav Gideon, Achuth Ajith Kumar, Yensani Prashanth Reddy, Shivraj Barath Kumar   +7 more
doaj   +2 more sources

Comments on “The Effect of Neoadjuvant Chemotherapy on Survival Outcomes in Patients With Variant Histologies Who Underwent Radical Cystectomy With Precystectomy Diagnostic Accuracy: A Multicenter Study of the Turkish Urooncology Association”

International Journal of Urology
We read with great interest the recent multicenter study by the Turkish Urooncology Association evaluating the impact of neo-adjuvant chemotherapy (NAC) on survival outcomes in patients with variant histologies of bladder cancer undergoing radical ...
Türker Soydas
exaly   +2 more sources

The signal transducer CD24 suppresses the germ cell program and promotes an ectodermal rather than mesodermal cell fate in embryonal carcinomas

Molecular Oncology, 2022
Testicular germ cell tumors (GCTs) are stratified into seminomas and nonseminomas. Seminomas share many histological and molecular features with primordial germ cells, whereas the nonseminoma stem cell population—embryonal carcinoma (EC)—is pluripotent ...
Margaretha A. Skowron, Teresa K. Becker, Lukas Kurz, Sina Jostes, Felix Bremmer, Florian Fronhoffs, Kai Funke, Gamal A. Wakileh, Melanie R. Müller, Aaron Burmeister, Thomas Lenz, Anja Stefanski, Kai Stühler, Patrick Petzsch, Karl Köhrer, Peter Altevogt, Peter Albers, Glen Kristiansen, Hubert Schorle, Daniel Nettersheim   +19 more
doaj   +2 more sources

Ventral corporal reinforcement using a pericardium allograft (Tutoplast®) in a patient undergoing urethrectomy procedure with an inflatable penile prosthesis in place: A case report

UroPrecision
Background Erectile dysfunction is a common consequence following radical cystectomy (RC), with inflatable penile prostheses (IPPs) placement considered as the gold standard for refractory cases.
Mohammed Mahdi, Shannon Leung, Curtis Pettaway, Run Wang   +3 more
doaj   +2 more sources

The effect of body mass index on oncological and surgical outcomes in patients undergoing radical cystectomy for bladder cancer: A multicentre study of the association of urooncology, Turkey

International journal of clinical practice, 2020
We aimed to evaluate the effect of body mass index (BMI) on oncological and surgical outcomes in patients who underwent radical cystectomy (RC) for bladder cancer (BC).
V. Izol, M. Değer, S. Baltacı, M. Akgul, I. Selvi, E. Ozden, E. Süer, Mustafa Zuhtu Tansug   +7 more
semanticscholar   +2 more sources

Prognostic impact of spatial niches in prostate cancer [PDF]

Scientific Reports
The formation of intratumoral spatial niches has been reported for many human malignancies. However, the translational potential of such spatial niches is understudied.
Felix Schneider, Sarah Heike Böning, Beatriz Coelho Antunes, Adam Kaczorowski, Magdalena Görtz, Viktoria Schütz, Johannes Huber, Albrecht Stenzinger, Markus Hohenfellner, Stefan Duensing, Anette Duensing   +10 more
doaj   +2 more sources

Extensive genotype-phenotype heterogeneity in renal cell carcinoma - a proof-of-concept study [PDF]

Frontiers in Oncology
BackgroundRenal cell carcinoma (RCC) is characterized by a high degree of genomic but also functional intratumoral heterogeneity (ITH). Mutations in VHL, chromatin remodeling genes such as SETD2 and genes that regulate the PI3K/AKT/mTOR pathway have been
Jakob Wieke, Christina Jurcic, Adam Kaczorowski, Sarah Böning, Martina Kirchner, Constantin Schwab, Viktoria Schütz, Markus Hohenfellner, Anette Duensing, Albrecht Stenzinger, Stefan Duensing   +10 more
doaj   +2 more sources

Region of interest localization, tissue storage time, and antibody binding density—a technical note on the GeoMx® Digital Spatial Profiler [PDF]

Immuno-Oncology and Technology
Background: Spatial biology is an emerging concept to interrogate tumor heterogeneity. The NanoString GeoMx® Digital Spatial Profiling (DSP) platform has become increasingly available. It combines high-plex analysis of protein or messenger RNA expression
S. Böning, F. Schneider, A.-K. Huber, D. Langhoff, H. Lin, A. Kaczorowski, A. Stenzinger, M. Hohenfellner, S. Duensing, A. Duensing   +9 more
doaj   +2 more sources

Targeting histone deacetylation, cell cycle regulators and heat shock proteins as novel therapeutic strategies for penile cancers [PDF]

npj Precision Oncology
Penile carcinoma (PeCa) is a rare malignancy occurring in men. Treatment typically involves penectomy, radiation, or cisplatin-based chemotherapy. A paclitaxel, ifosfamide, and cisplatin-based regimen achieves response rates around 65%.
Lara Marson, Margaretha A. Skowron, Pailin Pongratanakul, Mara Kotthoff, Gereon Poschmann, Hanibal Bohnenberger, Alexa Stephan, Meike M. Watolla, Elvira Mukinovic, Kai Stühler, Thomas Kurz, Hiresh Ayoubian, Johannes Linxweiler, Kerstin Junker, Daniel Nettersheim   +14 more
doaj   +2 more sources

Does the type of the previous biopsy affect the fusion prostate biopsy results? [PDF]

Prostate International
Background: It has been more than a decade since fusion prostate biopsy (FPB) has been used in the diagnosis of prostate cancer (PCa). Therefore, patients with a previous history of negative FPB and ongoing suspicion of PCa are beginning to emerge.
Gokhan Sonmez, Abdullah Golbasi, Unsal Bas, Emre C. Akınsal, Numan Baydilli, Sevket T. Tombul, Halil Tosun, Abdullah Demirtas, Deniz Demirci   +8 more
doaj   +2 more sources