Results 41 to 50 of about 1,483 (209)
Molecular and epigenetic pathogenesis of germ cell tumors
The development of germ cell tumors (GCTs) is a unique pathogenesis occurring at an early developmental stage during specification, migration or colonization of primordial germ cells (PGCs) in the genital ridge.
Melanie R. Müller +3 more
doaj +1 more source
Getting specific: participation preference in urooncological decision-making
Abstract Background Shared decision-making is the gold standard for good clinical practice, and thus, psychometric instruments have been established to assess patients’ generic preference for participation (e.g., the Autonomy Preference Index, API).
Büdenbender, Björn +5 more
openaire +4 more sources
Alternative therapeutic options targeting urologic malignancies, such as germ cell tumours, as well as urothelial, renal and prostate carcinomas, are still urgently needed. The membrane protein CD24 represents a promising immunotherapeutical approach. In this study, Daniel Nettersheim and colleagues demonstrate the therapeutic efficacy of using NK‐CD24‐
Christian Söhngen +13 more
wiley +1 more source
Prognostic significance of surgical margin status and gleason grade at the positive surgical margin in predicting biochemical recurrence after radical prostatectomy in a turkish patient cohort [PDF]
Objective: To investigate the prognostic role of positive surgical margin (PSM) features in addition to well-defined risk factors in predicting biochemical recurrence (BCR) after radical prostatectomy.
Koparal, Murat Yavuz +16 more
core +1 more source
Aims Testicular germ cell tumours are the most common solid malignancies in young men of age 14–44 years. It is generally accepted that both seminomas and non‐seminomas arise from a common precursor, the germ cell neoplasia in‐situ, which itself is the result of a defective (primordial) germ cell development.
Felix Bremmer +3 more
wiley +1 more source
Abstract Introduction Certain sociodemographic characteristics (e.g., older age) have previously been identified as barriers to patients' participation preference in shared decision‐making (SDM). We aim to demonstrate that this relationship is mediated by the perceived power imbalance that manifests itself in patients' negative attitudes and beliefs ...
Björn Büdenbender +5 more
wiley +1 more source
PubMedID: 21656469Purpose: To investigate the preferences and practice patterns of urooncologic surgeons in Turkey on bowel preparation and peri-operative management for radical cystectomy.
Cal C. +6 more
core +5 more sources
This study evaluated the interaction between germ cell tumors and their surrounding microenvironment. As such, the secretome has been analyzed to identify secreted factors, while transcriptome‐wide changes upon direct cell–cell interaction by means of 3D co‐cultures determined the deregulated gene sets. Subsequently, in vitro analyses were performed to
Margaretha A. Skowron +19 more
wiley +1 more source

