Results 61 to 70 of about 1,483 (209)

The Uro-oncology Patient and Vaccination Against SARS-CoV-2

European Urology Open Science, 2021
As of April 13, 2021, 137 million cases of COVID-19 and 2.95 million deaths have been reported worldwide. On December 21, 2020, the Pfizer-BioNTech vaccine was approved for use in the European Union, with efficacy of 95% protection against COVID-19 ...
Moises Rodriguez Socarrás, Juan Gómez Rivas, Jeremy Yuen-Chun Teoh, Javier Puente, Marco Moschini, Jesús Moreno-Sierra   +5 more
doaj   +1 more source

Molecular characterization of the CXCR4 / CXCR7 axis in germ cell tumors and its targetability using nanobody-drug-conjugates

Experimental Hematology & Oncology, 2023
Being stimulated by the chemokine CXCL12, the CXCR4 / CXCR7 cascade is involved in tumor proliferation, migration, and metastasis. The interaction between CXCL12, secreted by cells from the microenvironment, and its receptors is complex and has been ...
Gamal A. Wakileh, Philipp Bierholz, Mara Kotthoff, Margaretha A. Skowron, Felix Bremmer, Alexa Stephan, Stephanie M. Anbuhl, Raimond Heukers, Martine J. Smit, Philipp Ströbel, Daniel Nettersheim   +10 more
doaj   +1 more source

Targeting CLDN6 in germ cell tumors by an antibody-drug-conjugate and studying therapy resistance of yolk-sac tumors to identify and screen specific therapeutic options

Molecular Medicine, 2023
Background Being the standard-of-care for four decades, cisplatin-based chemotherapy is highly efficient in treating germ cell tumors (GCT). However, often refractory patients present with a remaining (resistant) yolk-sac tumor (YST(-R)) component ...
Margaretha A. Skowron, Mara Kotthoff, Felix Bremmer, Katja Ruhnke, Fatma Parmaksiz, Annika Richter, Stefan Küffer, Kirsten Reuter-Jessen, Stella Pauls, Anja Stefanski, Philipp Ströbel, Kai Stühler, Daniel Nettersheim   +12 more
doaj   +1 more source

Consensus in bladder cancer research priorities between patients and healthcare professionals using a four-stage modified Delphi method [PDF]

, 2019
We would like to thank the British Association of Urological Surgeons, British UroOncology Group, Action Bladder Cancer UK and Fight Bladder Cancer for their participation in this work.
Chatterton, Kathryn,, Van Hemelrijck, Mieke, Bryan, Richard, Enting, Deborah,, Kinsella, Netty,, Amery, Suzanne,, Nair, Rajesh,, Amery, Suzanne, Wylie, Harriet, Khan, Shamim, Bessa, Agustina,, Josephs, Debra,, Maclennan, Steven, Josephs, Debra, Chatterton, Kathryn, Hughes, Simon, Nair, Rajesh, Maclennan, Steven,, Enting, Deborah, Malde, Sachin, Wylie, Harriet,, Kinsella, Netty, Häggström, Christel,, Khan, Muhammad Shamim,, Cahill, Fidelma,, Häggström, Christel, Bessa, Agustina, Hughes, Simon,, Malde, Sachin,, Thurairaja, Ramesh,, Bryan, Richard,, Cahill, Fidelma, Bryan, Richard; id_orcid, Khan, Muhammad Shamim, Thurairaja, Ramesh, Van Hemelrijck, Mieke,   +35 more
core   +1 more source

Comparison of Laparoscopic and Open Partial Nephrectomy in Early-stage Kidney Masses

Journal of Urological Surgery
Objective: The aim of this study was to demonstrate our clinical experience on the impact of the choice between open partial nephrectomy (OPN) and laparoscopic partial nephrectomy (LPN) on achieving optimal oncological outcomes, perioperative parameters,
Turker Altuntas, Mohammad Yasir Sahak, Mehmet Umut Kutukoglu, Yiloren Tanidir, Ilker Tinay, Yusuf Senoglu, Tarik Emre Sener   +6 more
doaj   +1 more source

Immunotherapy Applications in Urology

Journal of Urological Surgery
Immunotherapy has transformed the management of urological cancers, offering renewed optimism for individuals diagnosed with bladder, kidney, and, to a lesser degree, prostate tumors. Conventional therapies, such as chemotherapy and radiation, frequently
Yusuf Şenoğlu, Bahadır Şahin
doaj   +1 more source

The Impact of the COVID-19 Pandemic on Urooncological Care and the Future

Bangladesh Journal of Urology, 2022
Abstract not available Bangladesh J. Urol.
openaire   +1 more source

Real‐world efficacy and toxicity of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma according to IMDC risk criteria—A multi‐center retrospective analysis on behalf of the GUARDIANS group

International Journal of Cancer, Volume 158, Issue 9, Page 2440-2451, 1 May 2026.
What's new? The combination of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma has demonstrated durable response and tolerability in clinical trials. However, inclusion criteria for clinical studies are restrictive, and patients in the real‐world setting tend to have more comorbidities.
Hendrik Dinkel, Linus Materna, Ramona Stelmach, Stefanie Zschäbitz, Stephanie Neuberger, Can D. Aydogdu, Jozefina Casuscelli, Timo Egenolf, Matteo Silberg, Julie Steinestel, Arne Strauss, Florian Kirchhoff, Marit Ahrens, Pia Paffenholz, Richard Cathomas, Berna C. Özdemir, Christopher Gossler, Philipp Ivanyi, Marc Rehlinghaus, Thomas Hilser, Viktor Grünwald, Katrin Schlack   +21 more
wiley   +1 more source

Multi‐Omics Signatures of Organ Clocks in Biological Aging and Disease: A Conceptual Framework for Organ‐Specific Aging Clocks

Aging Cell, Volume 25, Issue 5, May 2026.
Organ‐specific aging clocks integrating genomics, epigenomics, transcriptomics, proteomics, and metabolomics offer a more accurate assessment of biological aging than single‐omics approaches. This review proposes a multi‐omics framework emphasizing tissue data, longitudinal study designs, and clinically meaningful training outcomes to advance the ...
Maria Vasileiou, Gabor Liposits, Bara Barakat, Nam P. Nguyen   +3 more
wiley   +1 more source

Development of Home Health Services for Patients with Prostate, Kidney, and Adrenal Cancer in Türkiye

Gazi Medical Journal
Objective: Cancer detection rates are on the rise because of advances in technology, more widely used imaging methods, and the widespread implementation of screening tests.
Fatih Göksel, Erdem Öztürk, Numan Yıkılmaz   +2 more
doaj   +1 more source