Results 41 to 50 of about 12,135 (169)

The Synergy Between a Silver‐Ruthenium Antimicrobial and Aminoglycosides Is Based on Severe Macromolecular Damage

Molecular Microbiology, EarlyView.
AGXX enhances aminoglycoside activity against multidrug‐resistant pathogens such as uropathogenic Escherichia coli by increasing reactive oxygen species, causing protein aggregation and DNA damage. This effect is reduced by oxygen limitation or antioxidants. Polyphosphate protects cells from oxidative damage.
Emmanuel P. Oladokun, Gracious Y. Donkor, Julius K. Narh, Grady D. Jacobson, Cade Ward, Patrick O. Tawiah, Lisa K. Polzer, Kevin A. Edwards, Kyle A. Floyd, Jan‐Ulrik Dahl   +9 more
wiley   +1 more source

Promising Approach to Inhibit E. coli FimH Adhesion by C-Linked Mannosides

Proceedings, 2019
Antagonists of the uropathogenic Escherichia coli type-1 fimbrial adhesin (FimH) are recognized as attractive alternatives for antibiotic therapies and prophylactic strategies against acute and recurrent bacterial infections. [...]
Leila Mousavifar, René Roy
doaj   +1 more source

Discovery and antibacterial study of potential PPK1 inhibitors against uropathogenic E. coli

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Novel antibacterial agents are urgently needed to address the infections caused by multi-drug resistant bacteria. Urinary tract infections are common infectious diseases in clinical.
Liang Peng, Liting Zeng, Hongwei Jin, Lixin Yang, Yi Xiao, Ziquan Lan, Zhanpeng Yu, Shi Ouyang, Liangren Zhang, Ning Sun   +9 more
doaj   +1 more source

Cytologic, Clinicopathologic, and Histologic Findings in a Dog with a Gallbladder Neuroendocrine Carcinoma and Multiple Endocrinopathies

Veterinary Clinical Pathology, EarlyView.
ABSTRACT A 10‐year‐old spayed female Shih Tzu was evaluated for a gallbladder mass incidentally identified during a diagnostic workup for hyperadrenocorticism and persistent hypercalcemia. Diagnostic imaging revealed a vascularized intraluminal gallbladder mass, and cytologic examination showed cohesive clusters of epithelial cells with distinct ...
Sam Wicker, Alexis Johnson, Shelly Olin, Thomas Bevelock, Constance Fazio, Hiroyuki Mochizuki   +5 more
wiley   +1 more source

UropathogenicEscherichia coli-Associated Exotoxins [PDF]

Microbiology Spectrum, 2016
ABSTRACTEscherichia coliare a common cause of infectious disease outside of the gastrointestinal tract. Several independently evolvedE. coliclades are common causes of urinary tract and bloodstream infections. There is ample epidemiological andin vitroevidence that several different protein toxins common to many, but not all, of these strains are ...
openaire   +2 more sources

Characterization of Phylogroups, Virulence Factors and Antimicrobial Resistance in Canine Pyometra‐associated Escherichia coli

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study characterized 56 Escherichia coli isolates obtained from canine pyometra, which predominantly belonged to phylogroup B2 and harboured multiple virulence genes, with high multidrug resistance rates indicating potential clinical and zoonotic risks. ABSTRACT The presence of multidrug‐resistant extraintestinal pathogenic Escherichia coli (ExPEC)
İnci Başak Müştak, Murat Onur Yazlık, Beyza Nur Şitvan, Hamit Kaan Müştak, Ufuk Kaya   +4 more
wiley   +1 more source

Avian pathogenic Escherichia coli (APEC) and uropathogenic Escherichia coli (UPEC): characterization and comparison

The Journal of Infection in Developing Countries, 2021
Introduction: Avian pathogenic E. coli (APEC) and uropathogenic E. coli (UPEC) are responsible for avian colibacillosis and human urinary tract infections, respectively. There are genetic similarities between the APEC and UPEC pathotypes, suggesting the APEC strains could be a potential reservoir of virulence and antimicrobial-resistance genes for the ...
Daniela Tonini da Rocha, Felipe de Oliveira Salle, Karen Apellanis Borges, Thales Quedi Furian, Vladimir Pinheiro do Nascimento, Hamilton Luiz de Souza Moraes, Carlos Tadeu Pippi Salle   +6 more
openaire   +4 more sources

Beyond the Standard Antibiogram: Unveiling the Roles of pH and Salinity in Modulating Gentamicin Efficacy Against Escherichia coli in Urinary Tract Infections

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Modulation of the efficacy of gentamicin in urinary tract infections. ABSTRACT Urinary tract infections are highly prevalent diseases with a broad spectrum of clinical manifestations. This study investigates the influence of two key abiotic factors, pH and salinity, on the growth and antibiotic susceptibility of Escherichia coli ATCC 25922, Pseudomonas
Abdelwahab Rai, Mahdia El‐djohra El‐amina Saoud, Nesrine Tabchouche, Hamdi Bendif, Stefania Garzoli, Lotfi Mouni   +5 more
wiley   +1 more source

Biofilm and hemagglutinin formation: a Hallmark for drug resistant uropathogenic Escherichia coli

BMC Research Notes, 2019
Objective Urinary tract infection (UTI) is one of the most frequent disease encounters in pregnant mothers, and the most drug resistant, biofilm and hemagglutinin producer Uropathogenic Escherichia coli (UPEC) is the major etiologic agent. Therefore, the
Dawit Gebreegziabiher Hagos, Tadele Araya Mezgebo, Samuel Berhane, Araya Abraha Medhanyie   +3 more
doaj   +1 more source

Bacterial Profile of Urinary Tract Infections: Evaluation of Biofilm Formation and Antibiotic Resistance Pattern of Uropathogenic Escherichia coli

Journal of Pure and Applied Microbiology, 2020
Urinary tract infection (UTI) is one of the most common complaints in the outpatient clinic and a major health problem owing to the emergence of antibiotic resistance and biofilm formation.
Tariq Ahmad Shah, P. Preethishree, Ashwini, Vidya Pai   +3 more
doaj   +1 more source