Results 51 to 60 of about 5,120 (161)

Iron Necessity: The Secret of Wolbachia's Success? [PDF]

open access: yes, 2014
The bacterium Wolbachia (order Rickettsiales) is probably the world's most successful vertically-transmitted symbiont, distributed among a staggering 40% of terrestrial arthropod species. Wolbachia has great potential in vector control due to its ability
Darby, Alistair C   +2 more
core   +2 more sources

Metabolic Engineering of Saccharomyces cerevisiae for Fermentative Production of Heme

open access: yesBiotechnology Journal, Volume 19, Issue 10, October 2024.
Graphical Abstract and Lay Summary Heme is a key ingredient required to mimic the color and flavor of meat in plant‐based alternatives. Herein, the efficient synthesis of heme was achieved by reconstructing the heme biosynthetic pathway in S. cerevisiae.
Hyun‐Jae Lee   +4 more
wiley   +1 more source

Exploring current and emerging therapies for porphyrias

open access: yesLiver International, Volume 44, Issue 9, Page 2174-2190, September 2024.
Abstract Porphyrias are rare, mostly inherited disorders resulting from altered activity of specific enzymes in the haem synthesis pathway that lead to accumulation of pathway intermediates. Photocutaneous symptoms occur when excess amounts of photoreactive porphyrins circulate in the blood to the skin, whereas increases in potentially neurotoxic ...
Daniel Jericó   +7 more
wiley   +1 more source

Associated bacteria affect sexual reproduction by altering gene expression and metabolic processes in a biofilm inhabiting diatom [PDF]

open access: yes, 2019
Diatoms are unicellular algae with a fundamental role in global biogeochemical cycles as major primary producers at the base of aquatic food webs. In recent years, chemical communication between diatoms and associated bacteria has emerged as a key factor
Bilcke, Gust   +9 more
core   +2 more sources

The effect of altered pH growth conditions on the production, composition, and proteomes of Helicobacter pylori outer membrane vesicles

open access: yesPROTEOMICS, Volume 24, Issue 11, June 2024.
Abstract Gram‐negative bacteria release outer membrane vesicles (OMVs) that contain cargo derived from their parent bacteria. Helicobacter pylori is a Gram‐negative human pathogen that produces urease to increase the pH of the surrounding environment to facilitate colonization of the gastric mucosa.
Ella L. Johnston   +6 more
wiley   +1 more source

Congenital erythropoietic porphyria associated with myelodysplasia presenting in a 72-year-old man: report of a case and review of the literature [PDF]

open access: yes, 2003
Congenital erythropoietic porphyria (CEP) is a rare autosomal recessive disease owing to the deficient activity of uroporphyrinogen III synthase, the fourth enzyme in the porphyrin–haem synthetic pathway. Of the porphyrias, it is the most mutilating type,
Bichakjian, C.   +3 more
core   +1 more source

Risks for animal and human health related to the presence of polychlorinated naphthalenes (PCNs) in feed and food

open access: yesEFSA Journal, Volume 22, Issue 3, March 2024.
Abstract EFSA was asked for a scientific opinion on the risks for animal and human health related to the presence of polychlorinated naphthalenes (PCNs) in feed and food. The assessment focused on hexaCNs due to very limited data on other PCN congeners.
EFSA Panel name on Contaminants in the Food Chain (CONTAM)   +26 more
wiley   +1 more source

Crystal structure and substrate binding modeling of the uroporphyrinogen-III decarboxylase from Nicotiana tabacum. Implications for the catalytic mechanism.

open access: yesThe Journal of biological chemistry, 2001
The enzymatic catalysis of many biological processes of life is supported by the presence of cofactors and prosthetic groups originating from the common tetrapyrrole precursor uroporphyrinogen-III. Uroporphyrinogen-III decarboxylase catalyzes its conversion into coproporphyrinogen-III, leading in plants to chlorophyll and heme biosynthesis.
B M, Martins   +4 more
openaire   +1 more source

Biochemical Diagnosis of a Fatal Case of Günther’s Disease in a Newborn with Hydrops Foetalis [PDF]

open access: yes, 1993
Peer ...
Donner, C.   +10 more
core   +1 more source

Porphyrin biosynthesis in rhodopseudomonas palustris-V. Purification of porphyrinogen decarboxylase and some unusual properties [PDF]

open access: yes, 1986
1. 1. Uroporphyrinogen decarboxylase (EC 4.1.1.37) has been purified 16-fold from Rp. palustris to a specific activity of 210 nmol of total decarboxylated porphyrinogens III formed/hr per mg of protein and about 50% yield. The Rp.
del C. Batlle, A.M.   +2 more
core  

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