Results 1 to 10 of about 92,046 (305)

Comparison Between Urothelial and Non-Urothelial Urethral Cancer [PDF]

open access: yesFrontiers in Oncology, 2021
BackgroundTo test the effect of variant histology relative to urothelial histology on stage at presentation, cancer specific mortality (CSM), and overall mortality (OM) after chemotherapy use, in urethral cancer.Materials and MethodsWithin the ...
Mike Wenzel   +20 more
doaj   +6 more sources

Non-urothelial and urothelial variants of bladder cancer

open access: yesCancer Treatment and Research Communications, 2022
Non-urothelial bladder cancers make up a rare minority of all genitourinary (GU) tract histologic cancers since urothelial cancer (UC) makes up the most common histologic subtype.
Eun-mi Yu   +3 more
doaj   +3 more sources

Phases of tight junction barrier disruption during transurothelial migration of invasive urothelial cancer cells [PDF]

open access: yesScientific Reports
Bladder cancer is characterised by its multifocal nature and a high recurrence, yet the underlying mechanisms of these phenomena remain only partially understood. In the present study, we aimed to investigate transurothelial invasion of urothelial cancer
Tadeja Kuret   +5 more
doaj   +2 more sources

Supplementation of Probiotic Butyricicoccus pullicaecorum Mediates Anticancer Effect on Bladder Urothelial Cells by Regulating Butyrate-Responsive Molecular Signatures

open access: yesDiagnostics, 2021
In bladder cancer, urothelial carcinoma is the most common histologic subtype, accounting for more than 90% of cases. Pathogenic effects due to the dysbiosis of gut microbiota are localized not only in the colon, but also in regulating bladder cancer ...
Yen-Chieh Wang   +6 more
doaj   +1 more source

Highly Selective Anti-Cancer Activity of Cholesterol-Interacting Agents Methyl-β-Cyclodextrin and Ostreolysin A/Pleurotolysin B Protein Complex on Urothelial Cancer Cells. [PDF]

open access: yesPLoS ONE, 2015
Cholesterol content can vary distinctly between normal and cancer cells, with elevated levels in cancer cells. Here, we investigated cholesterol sequestration with methyl-β-cyclodextrin (MCD), and pore-formation with the ostreolysin A/pleurotolysin B ...
Nataša Resnik   +6 more
doaj   +1 more source

Urothelial Cancer Stem Cells [PDF]

open access: yesThe Scientific World JOURNAL, 2010
There is mounting evidence supporting the idea that tumors, similar to normal adult tissues, arise from a specific stem-like cell population, the cancer stem cells (CSCs), which are considered as the real driving force behind tumor growth, the ability to metastasize, as well as resistance to conventional antitumor therapy.
Irena Dimov   +2 more
openaire   +4 more sources

Bladder and upper urinary tract cancers as first and second primary cancers

open access: yesCancer Reports, 2021
Background Previous population‐based studies on second primary cancers (SPCs) in urothelial cancers have focused on known risk factors in bladder cancer patients without data on other urothelial sites of the renal pelvis or ureter.
Guoqiao Zheng   +5 more
doaj   +1 more source

Enfortumab Vedotin in urothelial cancer [PDF]

open access: yesTherapeutic Advances in Urology, 2020
The treatment landscape for metastatic urothelial cancer (mUC) beyond first-line platinum-based chemotherapy has changed significantly over the last 5 years with the recent approvals of the immune checkpoint inhibitors (ICIs), fibroblast growth factor receptor (FGFR) inhibitors and most recently Enfortumab Vedotin (EV).
Marie Alt   +4 more
openaire   +3 more sources

Elucidation of Novel Molecular Targets for Therapeutic Strategies in Urothelial Carcinoma: A Literature Review

open access: yesFrontiers in Oncology, 2021
Urothelial carcinoma therapy is a rapidly evolving and expanding field. Traditional cytotoxic chemotherapy regimens have not produced optimal long-term outcomes, and many urothelial cancer patients have comorbidities that disqualify them as chemotherapy ...
Blessie Elizabeth Nelson   +2 more
doaj   +1 more source

Mincle, an Innate Immune Receptor, Is Expressed in Urothelial Cancer Cells of Papillomavirus-Associated Urothelial Tumors of Cattle. [PDF]

open access: yesPLoS ONE, 2015
Mincle, macrophage-inducible C-type lectin, is a member of C-type lectin receptors. It plays an important role in anti-mycobacterial and anti-fungal immunity.
Sante Roperto   +7 more
doaj   +1 more source

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