Results 111 to 120 of about 92,046 (305)

Germline Variants in Bladder and Upper Tract Urothelial Cancers: Prevalence and Clinical Context in a Large Testing Registry

European Urology Open Science
Background and objective: The prevalence and clinical history of germline variants in bladder cancer and upper tract urothelial cancer (UTUC) remains incompletely defined, particularly regarding mismatch repair (MMR) and homologous recombination repair ...
Steven M. Monda, Eugene Oh, Patrick J. Lewicki, Samuel D. Kaffenberger, Tobias Else, Zachery R. Reichert, Irene Tsung, Khurshid R. Ghani, Charles B. Nguyen, Rob Humble, Matthew J. Schiewer, Robert Finch, Simpa Salami, Elena M. Stoffel, Todd M. Morgan, Thenappan Chandrasekar, Udit Singhal   +16 more
doaj   +1 more source

Long-Term Survival after Adrenalectomy for Asynchronous Metastasis of Bladder Cancer to the Bilateral Adrenal Glands

Case Reports in Urology, 2012
Isolated adrenal metastasis of bladder cancer, particularly the bilateral, is quite rare. Systemic chemotherapy is the treatment of choice for metastatic urothelial carcinoma.
S. Washino, M. Hirai, A. Matsuzaki, Y. Kobayashi   +3 more
doaj   +1 more source

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy

eLife, 2018
Current non-invasive approaches for detection of urothelial cancers are suboptimal. We developed a test to detect urothelial neoplasms using DNA recovered from cells shed into urine.
Simeon U Springer, Chung-Hsin Chen, Maria Del Carmen Rodriguez Pena, Lu Li, Christopher Douville, Yuxuan Wang, Joshua David Cohen, Diana Taheri, Natalie Silliman, Joy Schaefer, Janine Ptak, Lisa Dobbyn, Maria Papoli, Isaac Kinde, Bahman Afsari, Aline C Tregnago, Stephania M Bezerra, Christopher VandenBussche, Kazutoshi Fujita, Dilek Ertoy, Isabela W Cunha, Lijia Yu, Trinity J Bivalacqua, Arthur P Grollman, Luis A Diaz, Rachel Karchin, Ludmila Danilova, Chao-Yuan Huang, Chia-Tung Shun, Robert J Turesky, Byeong Hwa Yun, Thomas A Rosenquist, Yeong-Shiau Pu, Ralph H Hruban, Cristian Tomasetti, Nickolas Papadopoulos, Ken W Kinzler, Bert Vogelstein, Kathleen G Dickman, George J Netto   +39 more
doaj   +1 more source

MDNet: A Semantically and Visually Interpretable Medical Image Diagnosis Network

, 2017
The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods.
McGough, Mason, Xie, Yuanpu, Xing, Fuyong, Yang, Lin, Zhang, Zizhao   +4 more
core   +1 more source

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source

Variant isoforms of CD44 involves acquisition of chemoresistance to cisplatin and has potential as a novel indicator for identifying a cisplatin-resistant population in urothelial cancer

BMC Cancer, 2018
Background Cisplatin is the most commonly used chemotherapeutic agent in the treatment of patients with metastatic and/or recurrent urothelial cancer. However, the effectiveness of these treatments is severely limited due to the development of cisplatin ...
Masayuki Hagiwara, Eiji Kikuchi, Nobuyuki Tanaka, Takeo Kosaka, Shuji Mikami, Hideyuki Saya, Mototsugu Oya   +6 more
doaj   +1 more source

Causal Link Between Obstructive Uropathy, Estradiol, and Risk of Breast Cancer: Insights From Observational Evidence and Genetic Association Analyses

Medicine Advances, EarlyView.
Based on the observational analysis of UK Biobank clinical data, urinary tract obstruction showed a significant negative association with breast cancer risk, accompanied by substantially lower systemic estradiol levels in individuals with obstruction.
Hailu Wang, Yingying Dai, Wenhai Pan, Kaiyuan Mao, Zhiyi Zhang, Yan Zhang, Yifan Chen, Yiyin Zhang   +7 more
wiley   +1 more source

Incidence of Urinary Tract Infection After Combined Cystoscopy and Urodynamic Testing: A Prospective Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To evaluate the incidence of urinary tract infection (UTI) after combined cystoscopy and urodynamic testing. Methods A prospective analytical cohort study was conducted including adult patients undergoing cystoscopy, urodynamic testing, or both procedures during the same session at a quaternary referral center between May 1, 2023 ...
Camilo Andres Torres Sandoval, María Juliana Arcila, Andrés Duarte Osorio, Juan Guillermo Cataño, Sebastian Peña Rodriguez   +4 more
wiley   +1 more source

Clinical Assay of Serum SCC-Ag in Urothelial Cancers

The International Journal of Biological Markers, 1988
Serum squamous cell carcinoma related antigen (SCC-Ag) values were determined in 86 patients with urothelial cancers. Mean + standard deviation for serum SCC-Ag. was 3.4 ± 0.98 ng/ml and positive values (> 2.0 ng/ml) were found in 27%.
Y. Takahashi, I. Shinoda, T. Takeuchi, M. Kuriyama, Y. Ban, Y. Kawada   +5 more
doaj   +1 more source

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

UroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source