Results 121 to 130 of about 60,195 (236)

What Do We Know About Cyclooxygenases Expression in the Lower Urinary Tract of Dogs and Cats? A Systematic Review

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Cyclooxygenases (COX‐1 and COX‐2) are key enzymes in the biosynthesis of prostanoids, which mediate physiological functions, inflammation, and the process of carcinogenesis. In dogs and cats, lower urinary tract diseases are prevalent and often complex, requiring targeted therapeutic interventions.
Reiner Silveira de Moraes   +8 more
wiley   +1 more source

PD‐L1‐Inhibitor‐Associated Hidradenitis Suppurativa

open access: yes
Journal of Cutaneous Pathology, EarlyView.
Annie Jin   +2 more
wiley   +1 more source

Dermatological Adverse Events Associated With Lapatinib Treatment in Dogs With Urothelial Carcinoma: A Retrospective Study

open access: yesVeterinary Dermatology, EarlyView.
Lapatinib is widely used in human oncology; however, dermatological adverse events (DAEs) are common and have been correlated with treatment efficacy. In veterinary medicine, lapatinib use in combination with piroxicam has been shown to be effective in treating canine urothelial carcinoma (UC); however, the incidence and prognostic significance of DAEs
Kosuke Horita   +3 more
wiley   +1 more source

Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang   +4 more
wiley   +1 more source

Blood‐Based Circulating Tumor DNA Assays for Early Colorectal Cancer Detection: A Systematic Review of Performance in Asymptomatic Screening Populations

open access: yesInternational Journal of Cancer, Volume 159, Issue 4, Page 1028-1041, 15 August 2026.
Early detection of colorectal cancer via population‐based screening programs can reduce incidence and mortality, but current screening approaches are limited. This systematic review evaluated the screening potential of blood‐based circulating tumor DNA assays in asymptomatic screening populations.
Caroline Ledertoug Kahn   +4 more
wiley   +1 more source

When to Adjust for Multiple Testing: A Unifying Guiding Principle

open access: yesBiometrical Journal, Volume 68, Issue 4, August 2026.
ABSTRACT Most original articles published in the medical literature report the results of multiple statistical tests. In a few simple cases, there is agreement on whether to adjust for the number of performed tests. For many cases encountered in practice, however, this is less clear, and the recommendations in the literature are contradictory, along ...
Sabine Hoffmann   +8 more
wiley   +1 more source

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