Results 131 to 140 of about 60,195 (236)

TCF/LEF family transcription factors: Molecular landscape and prognostic scoring in pan‐cancer

open access: yesClinical and Translational Discovery, Volume 6, Issue 4, August 2026.
This study provides a comprehensive molecular landscape of TCF/LEF family transcription factors across 33 cancer types. We developed a TCF/LEF‐based prognostic score that correlates with immune infiltration, metabolic reprogramming and drug sensitivity, offering a robust transcriptomic signature for predicting patient survival and therapeutic response.
Zhengjun Yang   +8 more
wiley   +1 more source

A subset of high‐grade sarcomas with myogenic differentiation are associated with recurrent FGFR fusions

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Recurrent fusions involving FGFR1‐4 genes have been previously described in rare subsets of mostly benign chondroid and mesenchymal neoplasms involving bone and soft tissue. However, a more comprehensive analysis of sarcomas associated with FGFR fusions, including their incidence and histotypes, has not been performed.
Maximus CF Yeung   +4 more
wiley   +1 more source

Ectonucleotidases CD39 and CD73 expression levels are independent and inverse predictors of survival in muscle‐invasive bladder cancer

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Bladder cancer is one of the leading causes of cancer‐related mortality worldwide. Long‐term survival is particularly poor in patients with muscle‐invasive bladder cancer (MIBC). Modulation of purinergic signaling through the ectonucleotidases CD39 and CD73 has emerged as a promising therapeutic strategy in cancer medicine.
Stephan Ledderose   +5 more
wiley   +1 more source

Radiosurgery in Upper Tract Urothelial Carcinoma (UTUC). [PDF]

open access: yesCancers (Basel)
Staehler M   +12 more
europepmc   +1 more source

When disease travels downstream: The effect of intravesical recurrences in patients treated for upper tract urothelial carcinoma

open access: yesBJUI Compass, Volume 7, Issue 7, July 2026.
Abstract Background Treatment of upper tract urothelial carcinoma (UTUC) depends on risk stratification and tumour characteristics. Kidney‐sparing surgery (KSS) is preferred for low‐risk disease, whereas radical nephroureterectomy (RNU) is the standard for high‐risk UTUC.
Orlane J. A. Figaroa   +6 more
wiley   +1 more source

State of the nation: Understanding the current NHS treatment pathway to identify opportunities to advance future care of patients with high‐risk non‐muscle invasive bladder cancer in the UK (SPAN‐UK)

open access: yesBJUI Compass, Volume 7, Issue 7, July 2026.
Abstract Objectives This study aimed to understand clinical pathways for patients with high‐risk non‐muscle‐invasive bladder cancer (HR‐NMIBC) from diagnosis to follow‐up and to identify opportunities to improve care. Materials and Methods A cross‐sectional survey was conducted via structured online interviews with consented NHS healthcare ...
Jonathan Aning   +9 more
wiley   +1 more source

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