Results 141 to 150 of about 114,562 (319)

Treatment patterns, outcomes, and costs associated with localized upper tract urothelial carcinoma

open access: gold, 2021
Katherine E. Fero   +8 more
openalex   +1 more source

Long‐term outcomes following a 5‐year recurrence‐free interval in non‐muscle‐invasive bladder cancer

open access: yesBJU International, EarlyView.
Objective To describe the recurrence and progression trends of non‐muscle‐invasive bladder cancer (NMIBC) during a 14‐year period in Denmark between 2009 and 2022. Furthermore, to evaluate the risk of late recurrence with or without progression in patients who initially experience a 5‐year recurrence‐free interval (RFI).
Peter B. Hjort   +2 more
wiley   +1 more source

MP41-02 COMPARING CHANGES IN RENAL FUNCTION AFTER RADICAL SURGERY FOR UPPER TRACT UROTHELIAL CARCINOMA AND RENAL CELL CARCINOMA [PDF]

open access: bronze, 2016
Nirmish Singla   +5 more
openalex   +1 more source

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia   +6 more
wiley   +1 more source

KRAB Zinc‐Finger Protein ZNF205 Promotes Hepatocellular Carcinoma via p53 Pathway Repression

open access: yesCancer Science, EarlyView.
ZNF205 functions as a critical oncogenic regulator in hepatocellular carcinoma (HCC), where it interacts with p53 and functionally suppresses its transcriptional activity by competitively inhibiting p53 binding to target gene promoters. This p53 inactivation mechanism critically contributes to tumor progression in HCC. ABSTRACT The tumor suppressor p53
Xiaofen Huang   +15 more
wiley   +1 more source

CALR/HIF‐1α Positive Feedback Loop Drives CALR Upregulation to Promote EMT‐Mediated Bladder Cancer Progression via ROS/AKT Axis

open access: yesCancer Science, EarlyView.
This study first found that the high expression of CALR is due to a novel positive feedback loop with HIF‐1α in the tumor microenvironment: CALR stabilizes HIF‐1α protein, while HIF‐1α transcriptionally upregulates CALR expression, thereby self‐sustaining its high expression levels in BLCA.
Xintao Tian   +11 more
wiley   +1 more source

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