Results 101 to 110 of about 23,871 (225)

Age-related changes in afferent pathways and urothelial function in the male mouse bladder [PDF]

open access: yes, 2013
Key points •The prevalence of bladder conditions such as overactive bladder syndrome and urinary incontinence significantly increases with age, but how bladder function is altered by ageing is unclear.
Christopher Chapple   +7 more
core   +1 more source

Serum and Urine Nerve Growth Factor and Glycosaminoglycan Levels in Obstructive and Non‐Obstructive Feline Urolithiasis and Interstitial Cystitis

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Elevated NGF levels in serum and urine are associated with increased bladder inflammation and tissue damage in FIC cases. In contrast, reduced urinary GAG levels except in obstructive urolithiasis may contribute to bladder inflammation by enhancing urothelial permeability.
Mehmet Maden   +4 more
wiley   +1 more source

N–3 and n–6 polyunsaturated fatty acids induce cytostasis in human urothelial cells independent of p53 gene function

open access: yesJournal of Lipid Research, 2000
The role of long-chain polyunsaturated fatty acids (PUFA) in the etiopathology and treatment of cancer is poorly understood. We have studied the effects of n–3 and n–6 PUFA on the proliferation and survival of normal human uroepithelial (NHU) cells ...
Christine P. Diggle   +4 more
doaj   +1 more source

A pH-sensitive stearoyl-PEG-poly(methacryloyl sulfadimethoxine)-decorated liposome system for protein delivery: an application for bladder cancer treatment [PDF]

open access: yes, 2016
Stealth pH-responsive liposomes for the delivery of therapeutic proteins to the bladder epithelium were prepared using methoxy-poly(ethylene glycol)5kDa-1,2-distearoyl-sn-glycero-3-phosphoethanolamine (mPEG5kDa-DSPE) and stearoyl-poly(ethylene glycol ...
Balasso, Anna   +8 more
core   +1 more source

A role for epithelium‐derived 6‐nitrodopamine on human ureter contractility

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2360-2375, May 2026.
Abstract Background and Purpose To investigate the basal release of 6‐nitrodopamine (6‐ND) from human isolated ureter and the role of this novel catecholamine in the ureter contractility. Experimental Approach Ureters from 67 brain‐dead organ donors (40 males and 27 females) were used during kidney transplantation procedures.
Wilmar Azal Neto   +12 more
wiley   +1 more source

Phase II Study of Biweekly Plitidepsin as Second-Line Therapy for Advanced or Metastatic Transitional Cell Carcinoma of the Urothelium

open access: yesMarine Drugs, 2009
The objective of this exploratory, open-label, single-arm, phase II clinical trial was to evaluate plitidepsin (5 mg/m2) administered as a 3-hour continuous intravenous infusion every two weeks to patients with locally advanced/metastatic transitional ...
Sergio Szyldergemajn   +8 more
doaj   +1 more source

Bladder acellular matrix graft: in vivo functional properties of the regenerated rat bladder. [PDF]

open access: yes, 1999
The purpose of this study was to determine whether the rat urinary bladder augmented by an acellular matrix graft can restore the bladder's low-pressure reservoir function and preserve normal micturition.
Dahiya, R   +6 more
core  

Clitoral development in the mouse and human. [PDF]

open access: yes, 2020
The goal of this report is (a) to provide the first detailed description of mouse clitoral development, and (b) to compare mouse and human clitoral development.
Baskin, Laurence   +4 more
core   +1 more source

Animal Models of Hunner‐Type Interstitial Cystitis

open access: yesInternational Journal of Urology, Volume 33, Issue 5, May 2026.
ABSTRACT Background Animal models are crucial for mechanistic studies and therapeutic development of human diseases. At present, the etiology of interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic disease of the urinary bladder, remains undefined.
Yoshiyuki Akiyama, Yi Luo
wiley   +1 more source

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

open access: yesThe Journal of Physiology, Volume 604, Issue 9, Page 3611-3632, 1 May 2026.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy