Results 71 to 80 of about 28,025 (230)
Prognostic Factors for Transplant-Free Survival and Validation of Prognostic Models in Chinese Patients with Primary Biliary Cholangitis Receiving Ursodeoxycholic Acid [PDF]
OBJECTIVES: We aimed to validate the prognostic models for primary biliary cholangitis (PBC) in Chinese patients receiving ursodeoxycholic acid (UCDA), and to compare their performances in predicting the long-term survival. METHODS: Chinese patients with
Cheung, KS +4 more
core +1 more source
Immunosuppressive Therapy in Immune-Mediated Liver Disease in the Non-Transplanted Patient [PDF]
Autoimmune liver disease management goals are primarily slowing disease progression and symptomatic treatment. There are few options for curative medical management other than transplant for a spectrum of autoimmune liver disease that encompasses ...
Abhyankar, Anita +2 more
core +2 more sources
Changes in the gut microbiome during fasting‐induced molting and its effects on gut–liver function
During fasting, harmful microbiota and metabolites rise, triggering intestinal injury and activation of the TGF‐β signaling pathway, which enhances intestinal stem cell proliferation. Concurrently, hepatic function declines, indicated by increased hepatic and serum bile acids and upregulation of the non‐classical bile acid synthesis pathway.
Hao Zhang +11 more
wiley +1 more source
Background Ursodeoxycholic acid is the preferred first-line therapy for primary biliary cholangitis. Alternative therapies, such as obeticholic acid, are recommended for patients who cannot tolerate ursodeoxycholic acid or who have an inadequate response
Nicholas MacDonald +4 more
doaj +1 more source
Background: An epileptic seizure was defined as a transient occurrence of signs and symptoms due to abnormal excessive neuronal activity in the brain. A seizure lasting 30 minutes or longer or a series of seizures in which the patient did not regain
Zainab Adel Omran, Ahmed Hamed Jwied
doaj +1 more source
Separation of the glycine and taurine conjugates of ursodeoxycholic acid from those of lithocholic acid, chenodeoxycholic acid, deoxycholic acid, and cholic acid by thin-layer chromatography is described.
A K Batta, S Shefer, G Salen
doaj +1 more source
Controversies in the management of primary sclerosing cholangitis [PDF]
Primary sclerosing cholangitis (PSC) remains a rare but significant disease, which affects mainly young males in association with inflammatory bowel disease.
Devlin, J +4 more
core +1 more source
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
wiley +1 more source
Optimizing the Treatment of Atopic Dermatitis in Infants Using Ursodeoxycholic Acid
We have determined the advisability of including a suspension of ursodeoxycholic acid into the treatment of atopic dermatitis in infants. It is proved that taking a suspension of ursodeoxycholic acid in 25 infants with atopic dermatitis leads to a ...
O.H. Shadrin, H.A. Haiduchyk
doaj +3 more sources
Ursodeoxycholic acid lowers bile lithogenicity by regulating SCP2 expression in rabbit cholesterol gallstone models [PDF]
Aims: We designed this study to get insight into the disorder of lipid metabolism during cholesterol gallstone formation and evaluate the effect of ursodeoxycholic acid on the improvement of bile lithogenicity and on expression of lipid related genes ...
Cui, Naiqiang +4 more
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