Results 61 to 70 of about 28,025 (230)
Biological synthesis of ursodeoxycholic acid
Frontiers in Microbiology, 2023 Ursodeoxycholic acid (UDCA) is a fundamental treatment drug for numerous hepatobiliary diseases that also has adjuvant therapeutic effects on certain cancers and neurological diseases. Chemical UDCA synthesis is environmentally unfriendly with low yields.
Peng Song +8 more
doaj +1 more source
A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders
Clinical Pharmacology &Therapeutics, EarlyView.Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel +3 more
wiley +1 more source
Journal of Medical Case Reports, 2022 Background Congenital bile acid synthesis disorder type 3 caused by oxysterol 7α-hydroxylase deficiency is an extremely rare genetic liver disease. As it may cause rapid progression to end-stage liver disease, a high cautiousness in diagnosis and early ...
Weiqian Mo +7 more
doaj +1 more source
Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure [PDF]
, 2015 Hepatocellular carcinoma (HCC) is characterized by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which activates the unfolded protein response (UPR).
Ampe, Christophe +16 more
core +3 more sources
A case of idiopathic GGT elevation with acute hepatitis A
Journal of Family Medicine and Primary Care, 2019 Ursodeoxycholic acid modifies the bile acid pool and its effect on lowering liver enzymes is well documented in certain cases like chronic hepatitis but on the other hand it is known to worsen when given in advanced stages of liver disease.
Jaspreet Singh +2 more
doaj +1 more source
Galician Medical Journal, 2016 Non-alcoholic fatty liver disease is considered as an independent predictor of cardiovascular diseases which plays an important role in the development of ischemic heart disease. The drug most frequently used for treating this comorbidity is atorvastatin
Nataliya Karpyshyn
doaj +1 more source
Effect of phospholipids and bile acids on cholesterol nucleation time and vesicular/micellar cholesterol in gallbladder bile of patients with cholesterol stones [PDF]
, 1993 Supersaturation and rapid nucleation of cholesterol in bile are of key importance in the pathogenesis of cholesterol gallstones. While the effects of bile acids and phospholipids on cholesterol saturation of bile have been extensively studied, their ...
Huber, P. +4 more
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Ursodiol in Patients with Parenteral Nutrition–Associated Cholestasis [PDF]
, 2007 OBJECTIVE To review the role of ursodeoxycholic acid (ursodiol) in treating parenteral nutrition–associated cholestasis (PNAC). DATA SOURCES A MEDLINE (1950–May 2007) search was performed using the key terms parenteral nutrition, cholestasis ...
Btaiche, Imad F., San Luis, Valerie A.
core +1 more source
Zdorovʹe Rebenka, 2019 Background. Functional disorders of the gallbladder and sphincter of Oddi are highly relevant in pediatric gastroenterology. The purpose of the study was to improve the treatment for functional disorders of the gallbladder and sphincter of Oddi in ...
A.E. Abaturov, V.L. Babich
doaj +1 more source
Drug therapy of primary biliary diseases: classical and modern strategies [PDF]
, 2013 Definition: Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are both cholestatic liver diseases. A common feature of these disorders is the accumulation of bile acids in the liver and blood, presumably because of decreased ...
Leuschner, Ulrich, Schlichting, Julia
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