Investigating the combined effect of ursolic acid and alpelisib on inhibiting cell proliferation and the expression of HIF1α on 4T1 breast cancer cell line [PDF]
Journal of Research in Applied and Basic Medical Sciences, 2023 Background & Aims: Alpelisib and Ursolic acid are two compounds that have been shown to have potential as anti-cancer agents. Alpelisib is a selective inhibitor of the PI3K pathway, while Ursolic acid is a natural pentacyclic triterpene compound found ...
Erfan Sheikhi +2 more
doaj
In vitro evaluation of the comprehensive antimicrobial and antioxidant properties of Curtisia dentata (Burm.f) C.A. Sm: toxicological effect on the human embryonic kidney (HEK293) and human hepatocellular carcinoma (HepG2) cell lines [PDF]
, 2015 Curtisia dentata is used in African traditional medicine to treat variety of infections. C. dentata leaves were collected from Buffelskloof Nature Reserve, South Africa.
Fadipe, VO, Mongalo, NI, Opoku, AR
core +1 more source
Toxicological Research, 2021 Ursolic acid is a natural compound possessing several therapeutic properties including anticancer potential. In present study, cytotoxic and antimetastatic properties of ursolic acid were investigated in intestinal cancer cell lines INT-407 and HCT-116 ...
L. Rawat, V. Nayak
semanticscholar +1 more source
浙江大学学报. 农业与生命科学版, 2009 The optimum extraction process of ursolic acid from the fermentation product of Cornus officinalis was screened by the aid of ultrasonic, and the yield of ursolic acid was monitored by HPLC techniques.
XU Bai-tao +4 more
doaj +1 more source
Dispersive liquid–liquid microextraction and injection-port derivatization for the determination of free lipophilic compounds in fruit juices by gas chromatography-mass spectrometry [PDF]
, 2017 A method consisting of dispersive liquid–liquid microextraction (DLLME) followed by injection-port derivatization and gas chromatography-mass spectrometry (GC–MS) for the analysis of free lipophilic compounds in fruit juices is described.
Balcells Fluvià, Mercè +3 more
core +1 more source
Tigogenin and ursolic acid fromCestrum diurnum Linn. [PDF]
Experientia, 1964 AusCestrum diurnum Linn. wurden Ursolsaure und Tigonin, [α]D23 −48° (Pyridine) und aus Tigonin Tigogenin durch Hydrolyse isoliert bzw. erhalten.
R N, Chakravarti, S, Datta, M N, Mitra
openaire +2 more sources
AnimalsMuscle atrophy and weakness are prevalent and debilitating conditions in dogs that cannot be reliably prevented or treated by current approaches. In non-canine species, the natural dietary compound ursolic acid inhibits molecular mechanisms of muscle ...
Scott M. Ebert +10 more
doaj +1 more source
Mediators of Inflammation, 1994 The authors have previously isolated and purified ursolic acid from heather flowers (Calluna vulgarts). This terpene was found to inhibit HL-60 leukaemic cell proliferation and arachidonic acid oxidative metabolism in various cell species. The effects of
D. Es-Saady +5 more
doaj +1 more source
Heliyon, 2019 The present study discusses the isolation of ursolic acid from the chloroform extract of Paulownia tomentosa (Thunb) Steud fruits and its cytotoxic effect has been assessed in-vitro was performed in different cells lines (A-549, MCF-7, HepG2) and in-vivo
Sanaa A. Ali +4 more
doaj +1 more source
Ursolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathways [PDF]
, 2012 10.1371/journal.pone.0032476PLoS ...
Ho, P.C. +7 more
core +5 more sources