Results 191 to 200 of about 698,130 (295)

Identifying and Prioritizing Age-Friendly Design Principles and Guidelines for Developing Transportation Planning E-Tools: Scoping Review. [PDF]

JMIR Aging
Bahrampoor Givi S, Gagnon-Roy M, Provencher V.   +2 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Usability testing of an upper-extremity rehabilitation robot for stroke rehabilitation. [PDF]

BMC Neurol
Lin Y, Wang H, Ding L, Qu Q, Fu J, Lin Y, Gu J, Huang Y, Jia J.   +8 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Spanish Version of the mHealth App Usability Questionnaire (S-MAUQ): Translation, Adaptation, and Validation Study.

JMIR Mhealth Uhealth
Carrillo-León AL, Falgueras-Cano J, Díaz-Mohedo E.   +2 more
europepmc   +1 more source

Assessment of Telemedicine Perceptions, Usability, and Implementation Barriers Among Physicians in Kazakhstan Using the Telehealth Usability Questionnaire-Model for Assessment of Telemedicine-Kazakhstan Version (TUQ-MAST-KZ) Questionnaire: Pilot Cross-Sectional Survey Study. [PDF]

JMIR Form Res
Kenessova K, Anartayeva M, Кеmelbekov K, Seidakhmetova A, Kushkarova A, Rysbekov T, Sultangaziyeva A.   +6 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Chatbot Usability Scale in Chinese Users: Cross-Cultural Adaptation and Validation Study.

JMIR Hum Factors
Ma H, Pei R, Li S, Wang A, Tang X, Piao M.   +5 more
europepmc   +1 more source

Usability Evaluation of a Central Monitoring System with AI-Based Cardiac Arrest Prediction in the ICU. [PDF]

J Clin Med
Oh J, Kim Y, Jang W.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source