Results 131 to 140 of about 119,123 (311)

Access and usability issues of scholarly electronic publications

, 2004
This chapter looks at the various access and usability issues related to scholarly information resources. It first looks at the various channels through which a user can get access to scholarly electronic publications.
Chowdhury, G., Chowdhury, GG
core  

Exploring usability discussions in open source development

, 2005
The public nature of discussion in open source projects provides a valuable resource for understanding the mechanisms of open source software development. In this paper we explore how open source projects address issues of usability.
Nichols, David M., Twidale, Michael B.
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Towards a Refined Heuristic Evaluation: Incorporating Hierarchical Analysis for Weighted Usability Assessment

Big Data and Cognitive Computing
This study explores the implementation of the analytic hierarchy process in usability evaluations, specifically focusing on user interface assessment during software development phases.
Leonardo Talero-Sarmiento, Marc Gonzalez-Capdevila, Antoni Granollers, Henry Lamos-Diaz, Karine Pistili-Rodrigues   +4 more
doaj   +1 more source

Usability Evaluation of Learning Management Systems in Sri Lankan Universities

, 2015
As far as Learning Management System is concerned, it offers an integrated platform for educational materials, distribution and management of learning as well as accessibility by a range of users in cluding teachers, learners and content makerses ...
Achchuthan, S., Kuhanesan, Thuseethan, S.   +3 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Capturing Usability Problems for People Living With Dementia by Applying the DEMIGNED Principles in Usability Evaluation Methods: Mixed Methods Study

JMIR Human Factors
BackgroundDementia-related impairments can cause complex barriers to access, use, and adopt digital health technologies (DHTs). These barriers can contribute to digital health inequities.
Thomas Engelsma, Simone Heijmink, Heleen M A Hendriksen, Leonie N C Visser, Afina W Lemstra, Monique W M Jaspers, Linda W P Peute   +6 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Usability evaluation of an academic library website

Pakistan Journal of Information Management & Libraries, 2012
The focus of the study was the usability evaluation of the Punjab University Library (PUL) website. The main objectives of the study were to ascertain the feelings of website users along with the efficiency of the system with reference to its goals and ...
Memoona Iqbal, Nosheen Fatima Warraich
doaj