Results 141 to 150 of about 119,123 (311)

Usability testing for improving interactive geovisualization techniques

open access: yes, 2002
Usability describes a product’s fitness for use according to a set of predefined criteria. Whatever the aim of the product, it should facilitate users’ tasks or enhance their performance by providing appropriate analysis tools.
Tobon, Caroline
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

User experience evaluation of Cogscreen for screening mild cognitive impairment: Formative and summative evaluation

open access: yesDigital Health
Background Mild cognitive impairment (MCI) is an early stage of cognitive decline and a key risk factor for dementia. Early detection is essential for timely intervention and prevention, so various digital screening tools have been developed recently ...
Eunji Hwang   +9 more
doaj   +1 more source

Aesthetic and symbolic aspects versus usability: Evaluation of daily use product - lemon squeezer

open access: yes, 2012
Usability has been characterized as a requirement in the development of product design. Besides the physical aspects, the subjects’ perception and their relationship with objects of daily use have been the focus of research in usability.
de Mattos, Liara Mucio [UNESP]   +5 more
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Towards an Enhanced User Experience with Smart Phone Weather Alert Applications: Usability and User-Centered Design Approaches [PDF]

open access: yes, 2018
Today, smart phones are ubiquitous in our everyday lives. We rely heavily on their immediately available features, especially when time-critical and/or life-saving information, such as weather alert messages, need to be easily and quickly accessed.
Khamaj, Abdulrahman Mousa
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Evaluation Insights to Key Processes of Digital Repositories [PDF]

open access: yes, 2010
Digital repositories are considered essential information tools for scholarly communication. Their acceptability and extensive use by communities and institutions, as well as the users’ commitment in self-archiving, highlight the need for developing ...
Tsakonas, Giannis   +2 more
core  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy