Results 151 to 160 of about 665,180 (356)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Less is more: what design against crime can contribute to sustainability. [PDF]

open access: yes, 2008
Crime is a voracious form of premature obsolescence. Replacement of insured stolen items increases levels of product consumption that are unsustainable.
Gamman, Lorraine, Thorpe, Adam
core  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Applying Human-Centered Design Methods in Industry – a Field Report [PDF]

open access: yes, 2016
Human-centered design methods are nowadays widely used in the design of consumer products. These methods aim at designing products with a high usability and a positive user experience (UX).
Büttner, Sebastian   +2 more
core  

User-Centered Design and Interactive Health Technologies for Patients [PDF]

open access: green, 2009
Annette De Vito Dabbs   +6 more
openalex   +1 more source

User centered passive building design [PDF]

open access: yes, 2013
The full integration of End User Factors (EUFs) into the building design processes environment is still emergent. It has been suggested from other sectors that the integration of EUFs into design can improve work performance and promote the workforce’s physical and mental health.
openaire   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

User-Centered Design and Evaluation – The Big Picture [PDF]

open access: bronze, 2009
Victoria Bellotti   +3 more
openalex   +1 more source

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