Results 51 to 60 of about 715,050 (330)

After the editing is done: Designing a Graphic User Interface for digital editions

open access: yesDigital Medievalist, 2012
With its origins dating back only to the second half of the twentieth century, Computer Science can be considered a very young discipline. The widespread adoption of the "Personal Computer" is even more recent. Introduced in the 1970s, its ascendancy was
Roberto Rosselli Del Turco
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

The Berlin Brain-Computer Interface: Machine Learning Based Detection of User Specific Brain States

open access: yesJournal of universal computer science (Online), 2006
The Berlin Brain-Computer Interface (BBCI) project develops an EEG-based BCI system that uses machine learning techniques to adapt to the specific brain signatures of each user.
B. Blankertz   +5 more
semanticscholar   +1 more source

User Interface Aspects of a Human-Hand Simulation System [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2005
This paper describes the user interface design for a human-hand simulation system, a virtual environment that produces ground truth data (life-like human hand gestures and animations) and provides visualization support for experiments on computer vision ...
Beifang Yi   +3 more
doaj  

Spud 1.0: generalising and automating the user interfaces of scientific computer models [PDF]

open access: goldGeoscientific Model Development, 2009
The interfaces by which users specify the scenarios to be simulated by scientific computer models are frequently primitive, under-documented and ad-hoc text files which make using the model in question difficult and error-prone and significantly increase
David A. Ham   +9 more
openalex   +3 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

An Adaptive Brain Actuated System for Augmenting Rehabilitation

open access: yesFrontiers in Neuroscience, 2014
For people living with paralysis, restoration of hand function remains the top priority because it leads to independence and improvement in quality of life.
Scott Alan Roset   +3 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Database Graphic User Interface correspondence with Ellis Information Seeking behavior Model

open access: yesIranian Journal of Information Processing & Management, 2010
Graphic User interface serves as a bridge between man and databases. Its primary purpose is to assist uses by establishing interaction with computer systems.
Muhammad Azami, Rahmatullah Fatahi
doaj  

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