Results 101 to 110 of about 188,183 (294)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Effects of Customer Value, Customer Experience and Utilitarian Value toward Repurchase Interest
Proceedings of the 2019 International Conference on Organizational Innovation (ICOI 2019), 2019 his article aims to test and analyze the effect of customer value, customer experience and utilitarian value toward repurchase interest at the Beauty Clinic. This article is an explanatory research. The population in this article is all consumers who have purchased products more than twice in the Beauty Clinic with a sampling technique using purposive ...
WULANDARI, Deasy, NUDIN, Intan Aprillia
openaire +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
SHOPPERS’ LOYALTY IN PASAR DUKUH MENANGGAL
Jurnal Manajemen dan Wirausaha, 2013 This study improved the antecedents of loyalty such as price sensitivity, shopping values (utilitarian values and hedonic values) and satisfaction in Pasar Dukuh Menanggal Surabaya. It consists of 145 respondents and the result tested by SEM.
Anastasia Audrey Oenaryo +1 more
doaj
Pareto-Optimal Allocation of Indivisible Goods with Connectivity Constraints
, 2018 We study the problem of allocating indivisible items to agents with additive valuations, under the additional constraint that bundles must be connected in an underlying item graph.
Igarashi, Ayumi, Peters, Dominik
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Muslim consumers’ attitudes toward the advertisement of non-certified coffee shops [PDF]
, 2016 In Malaysia, the Halal logo and certification has a significant religious cue that might peripherally generate a favourable attitude towards advertisement among Muslims. Prior findings have stated that Islamic religious symbol influenced Muslim consumers’
Ishak Ismail, +2 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source