Results 61 to 70 of about 726,175 (291)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Topical Ajwa date (Phoenix dactylifera L.) extract cream modulates fibroblast proliferation in UV-B-Exposed Wistar rats: Effects on TNF-alpha and SOD levels

open access: yesJurnal Teknologi Laboratorium
Humans always want to look attractive and youthful, in order to increase self-confidence, so they make efforts to avoid the appearance of signs of aging by slowing down and preventing the aging process.
Sri Mahoni   +2 more
doaj   +1 more source

UV-B induced accumulation of tocopherol in Arabidopsis thaliana is not dependent on individual UV photoreceptors

open access: yesPlant Stress, 2022
Tocopherols are lipophilic antioxidants in plants. Their potential role in protecting UV-B exposed plants has been alluded to, but not shown. Here we have determined UV-B induced accumulation of tocopherol in the model plant Arabidopsis thaliana and ...
Uthman O. Badmus   +4 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Impact of UV-B on drought- or cadmium-induced changes in the fatty acid composition of membrane lipid fractions in wheat [PDF]

open access: yes, 2014
UV-B radiation may have either a positive or negative impact under the same conditions in wheat, depending on the type of secondary abiotic stressor: Cd or drought. Supplemental UV-B prevented the wilting and leaf rolling induced by PEG treatment.
Gondor, Orsolya Kinga   +4 more
core   +1 more source

Synthesis and crystallization of configurable TiO2 nanostructures through anodization process of moderate concentration of NH4F-based organic electrolyte

open access: yesMaterials Research Express
TiO _2 nanostructures play a crucial role in various applications, and optimizing their synthesis is essential for tailoring their properties. Herein, we report the anodization of Ti foils using an electrolyte with a mid-high NH _4 F concentration to ...
Marcos Luna-Cervantes   +2 more
doaj   +1 more source

Involvement of the eIF2α Kinase GCN2 in UV-B Responses

open access: yesFrontiers in Plant Science, 2019
GCN2 (general control nonrepressed 2) is a serine/threonine-protein kinase that regulates translation in response to stressors such as amino acid and purin deprivation, cold shock, wounding, cadmium, and UV-C exposure. Activated GCN2 phosphorylates the α-
Paula Llabata   +9 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Photoreceptor cross-talk in UV-B photomorphogenesis in tomato (Solanum lycopersicum) : screening through phytochrome and cryptochrome mutants : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Plant Biology at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2017
Figures 1.1, 1.3, 1.4 and 1.5 removed due to copyright reasonsPlant photoreceptors detect changes in the light environment and induce differential gene expression, resulting in the appropriate physiological and morphological responses.
Pabellon, Ivie V S
core  

Cumulative abiotic stresses and their effect on the antioxidant defense system in two species of wheat, Triticum durum Desf and Triticum aestivum L. [PDF]

open access: yes, 2013
The combined effects of heat and UV-B on the antioxidant system and photosynthetic pigments were investigated in the leaves of T. durum Desf. and Triticum aestivum L.
Al-Ghamdi A.A.   +2 more
core   +1 more source

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