Results 101 to 110 of about 80,730 (306)

Tapinarof as a Therapeutic Aryl Hydrocarbon Receptor‐Modulating Agent in the Treatment of Atopic Dermatitis

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji   +7 more
wiley   +1 more source

The Inhomogeneous Ionizing Background Following Reionization

open access: yes, 2009
We study the spatial fluctuations in the hydrogen ionizing background in the epoch following reionization (z ~ 5--6). The rapid decrease with redshift in the photon mean free path (m.f.p.), combined with the clustering of increasingly rare ionizing ...
Andrei Mesinger   +46 more
core   +1 more source

A multi‐trait evaluation of patterns and fitness consequences of breeding phenology plasticity with nocturnal warming and food restriction in a lizard

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Faced with climate warming, ectothermic species shift their breeding phenology, which is in part attributed to an acceleration of gestation or incubation in warmer environments.
Théo Bodineau   +7 more
wiley   +1 more source

Involvement of NADPH oxidase 1 in UVB-induced cell signaling and cytotoxicity in human keratinocytes

open access: yesBiochemistry and Biophysics Reports, 2018
Members of NADPH oxidase (Nox) enzyme family are important sources of reactive oxygen species (ROS) and are known to be involved in several physiological functions in response to various stimuli including UV irradiation.
Azela Glady   +4 more
doaj   +1 more source

Shrubs inhibit plant diseases by intercepting light in alpine meadows

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Climate change is disproportionately impacting mountain ecosystems, leading to widespread shrub expansion into alpine meadows. Shrub encroachment alters the albedo, carbon budget and warming rate in alpine grasslands, but it remains challenging to predict how shrub ...
Yimin Zhao   +5 more
wiley   +1 more source

A Perspective on the Use of NB-UVB Phototherapy vs. PUVA Photochemotherapy

open access: yesFrontiers in Medicine, 2018
Narrowband UVB (NB-UVB) phototherapy and psoralen-UVA (PUVA) photochemotherapy are widely used phototherapeutic modalities for a range of skin diseases.
Sally H. Ibbotson
doaj   +1 more source

The Opacity of the Intergalactic Medium Measured Along Quasar Sightlines at $z\sim 6$

open access: yes, 2018
We publicly release a new sample of $34$ medium resolution quasar spectra at $5.77\leq z_{\rm em}\leq6.54$ observed with the Echellette Spectrograph and Imager (ESI) on the Keck telescope.
Davies, Frederick B.   +2 more
core   +1 more source

Vitiligoda dar uvb, kalsipotriol-dar band uvb, betametazon-kalsipotriol-dar band uvb kombinasyon tedavilerinin etkinliğinin karşılaştırılması

open access: yes, 2021
Background: Vitiligo is an idiopathic, acquired, well-demarcated disorder characterized by depigmented macules. There are clinical variants of localized, generalized, universal and mixed types. Photochemotherapy is the most commonly used treatment modality in generalized vitiligo.
openaire   +1 more source

Colour Morphs as Alternative Solutions to the Trade‐Off Predicted by the Immuno‐Competence Handicap Hypothesis

open access: yesIntegrative Zoology, EarlyView.
In this study, we tested whether white and yellow morphs of the common wall lizard (Podarcis muralis) adopt alternative strategies shaped by the immuno‐competence handicap hypotheses (ICHH). We found that testosterone‐induced immune suppression was stronger in white males, while aggression decreased in both morphs.
Roberto Sacchi   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy