Results 131 to 140 of about 25,326 (255)

Topical Mitomycin C Chemotherapy After Surgical Resection of Conjunctival Amelanotic Melanoma in a Dog

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective To describe the clinical course and outcome of adjuvant topical mitomycin C (MMC) therapy following incomplete resection of a conjunctival amelanotic melanoma in a dog. Animals Studied A 15‐year‐old spayed‐female Shih Tzu presented with a conjunctival mass in the right eye (OD).
Junyeong Ahn, Koangyong Sung, Minwoo Jang, Kangmoon Seo, Seonmi Kang   +4 more
wiley   +1 more source

A melanoma subtype: Uveal melanoma [PDF]

Journal of the American Academy of Dermatology, 2011
Julia, Wu, Georg, Brunner, Julide Tok, Celebi   +2 more
openaire   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, Volume 20, Issue 6, Page 1612-1625, June 2026.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain

Advanced Materials, Volume 38, Issue 32, 8 June 2026.
A radiofrequency antenna platform comprising planar and bend configurations is developed, incorporating structurally integrated epsilon‐negative metamaterial unit cells to enhance MRI. These antennas enable high‐resolution in vivo human MRI of the eye, orbit, and occipital brain. Comprehensive validation, including simulations, phantom experiments, SAR,
Nandita Saha, Bilguun Nurzed, Mostafa Berangi, Andre Kuehne, Helmar Waiczies, Igor Fabian Tellez Ceja, Xiang Hu, Thomas Gladytz, Lisa Krenz, Dave Huebler, Beate Endemann, Claudia Brockmann, Ebba Beller, Oliver Stachs, Thoralf Niendorf   +14 more
wiley   +1 more source

The genetics of uveal melanoma: an emerging framework for targeted therapy

, 2012
Uveal melanoma is the second most common form of melanoma and the most common primary intraocular malignancy. Until recently, very little was known about the genetics of this aggressive cancer. Mutations in oncogenes and tumor suppressors that are common
Harbour, J William
core   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, Volume 13, Issue 35, 24 June 2026.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, Volume 13, Issue 35, 24 June 2026.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Uveal Prolapse Following Cataract Extraction Simulating Melanoma

, 2008
Prolapsed uveal tissue through a cataract incision can simulate any pigmented epibulbar mass, including conjunctival melanoma, extraocular extension of a ciliary body or choroidal melanoma, and pigmented squamous cell carcinoma of the conjunctiva.
Materin, Miguel A., Carol L. Shields, Samuray Tuncer, Shields, Carol L., Marr, Brian P., Brian P. Marr, Shields, Jerry A., Miguel A. Materin, Jerry A. Shields, TUNCER, Samuray   +9 more
core   +1 more source

Current and emerging treatment options for uveal melanoma

, 2013
Patricia Rusa Pereira,1 Alexandre Nakao Odashiro,2 Li-Anne Lim,1 Cristina Miyamoto,1 Paula L Blanco,4 Macanori Odashiro,3 Shawn Maloney,1 Dominique F De Souza,1 Miguel N Burnier Jr1 1The Henry C Witelson Ocular Pathology Laboratory, McGill University ...
Miyamoto C, Blanco PL, De Souza DF, Odashiro M, Pereira PR, Lim L, Odashiro AN, Maloney S, Burnier Jr MN   +8 more
core  

A rare case of leptomeningeal carcinomatosis in a patient with uveal melanoma: case report and review of literature

, 2016
Uveal melanoma is a rare subtype of melanoma, accounting for only 3–5% of all melanoma cases in the USA. Although fewer than 4% of uveal melanoma patients present with metastasis at diagnosis, approximately half will develop metastasis, more than 90% of ...
Harbour, J. William, Linda McIntosh, Forsyth, Peter A, Magliocco, Anthony, Arnold Etame, Evernden, Brittany, Brittany Evernden, Rajappa S. Kenchappa, Keiran S.M. Smalley, Peter A. Forsyth, Sahebjam, Solmaz, Solmaz Sahebjam, Puskas, John, Inna V. Fedorenko, Fedorenko, Inna V, Gisela Caceres, Ryzhova, Elena, McIntosh, Linda, Etame, Arnold, Smalley, Keiran S.M, Elena Ryzhova, John Puskas, Caceres, Gisela, Anthony Magliocco, J. William Harbour, Kenchappa, Rajappa S   +25 more
core   +1 more source