Results 81 to 90 of about 43,652 (215)

Precision medicine in cutaneous melanoma—A comprehensive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Precision medicine tailors treatment to each patient, beginning with detailed diagnostics. In melanoma, it has advanced considerably: Some methods are in practice and guidelines, while others are commercially available but not routine. This review highlights current and emerging approaches, including molecular profiling, imaging, biomarkers and AI ...
Markus Reitmajer, Lukas Flatz
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet, Belén Pepió‐Tárrega, Javier Saiz‐Poseu, Alba López‐Moral, Faiz Ullah, Victor J. Yuste, Daniel Ruiz‐Molina, Salvio Suárez‐García   +7 more
wiley   +2 more sources

Posterior uveal melanoma in adolescents and children: current perspectives

Clinical Ophthalmology, 2018
Matthew V Fry,1 James J Augsburger,1 June Hall,2 Zélia M Corrêa21Department of Ophthalmology, College of Medicine, University of Cincinnati, Cincinnati, OH, USA; 2Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore ...
Fry MV, Augsburger JJ, Hall J, Corrêa ZM   +3 more
doaj  

Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques. [PDF]

, 2019
Choroidal melanocytes (HCMs) are melanin-producing cells in the vascular uvea of the human eye (iris, ciliary body and choroid). These cranial neural crest-derived cells migrate to populate a mesodermal microenvironment, and display cellular functions ...
Cherepanoff, Svetlana, Conway, Robert Max, Gratton, Enrico, Macmillan, Alexander, Madigan, Michele C, Sitiwin, Ephrem, Whan, Renee   +6 more
core  

Evaluating VEGFR2 as a Target for Anti‐Tumour Therapy in Canine Melanoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Vascular endothelial growth factor receptor 2 (VEGFR2) is a key target for anti‐angiogenic oncotherapy, as inhibiting this receptor on tumour vasculature slows tumour development and enhances drug‐ and immune infiltration, improving therapy outcome.
Esther Hindriks, Wilhelmina Bergmann, Aitor Martínez Ruiz, Maurice M. J. M. Zandvliet, Alice J. A. M. Sijts, Femke Broere   +5 more
wiley   +1 more source

T Cell-Engaging Bispecific Antibodies Targeting gp100 and PRAME: Expanding Application from Uveal Melanoma to Cutaneous Melanoma

Pharmaceutics
Uveal melanoma represents a rare and aggressive subtype of melanoma with limited treatment options and poor prognosis, especially in the metastatic setting.
Robin Reschke, Alexander H. Enk, Jessica C. Hassel   +2 more
doaj   +1 more source

Genetic Prognostic Factors and Follow-up in Uveal Melanoma [PDF]

, 2012
An important part of oncological research is to identify prognostic factors and predict which patients are at risk for (early) metastasis. This thesis aims to describe the known genetic alterations in uveal melanoma and define new chromosomal regions and
Bosch, T. (Thomas) van den
core  

Prevalence of ocular and oculodermal melanocytosis in Spanish population with uveal melanoma [PDF]

, 2012
Producción CientíficaThe aim of this study was to determine the prevalence of ocular and oculodermal melanocytosis (ODM) among patients with uveal melanoma (UM) in a Spanish population.
A Almaraz, AD Singh, AD Singh, AK Leung, C Garcia-Alvarez, C Teekhasaenee, CL Shields, E Carreño, F Lopez-Lara, G Virgili, GP Yu, H Kiratli, HJ Sagar, IW McLean, J M De Frutos-Baraja, JA Shields, JA Shields, JR Gonder, JR Gonder, JR Gonder, LH Sobin, M A Saornil, M Ota, M Yanoff, N Velazquez, P Theunissen, SG Honavar, TB Fitzpatrick   +27 more
core   +2 more sources

A Comparative Study of Melanocytic Tumours: Linking Portuguese Dogs and Cats to Human Cases

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Melanocytic tumours (MT) occur in both humans and companion animals, presenting an opportunity for comparative oncology research. Thus, this study provides a comprehensive epidemiological analysis comparing MT in Portuguese dogs, cats and humans. Data were obtained from the Portuguese National Cancer Registry (RON) (2011–2021) and Vet‐OncoNet (
Catarina Alves Pinto, Ana Isabel Ribeiro, João Niza‐Ribeiro, Carlos Alberto Palmeira de Sousa, Katia Pinello, Andreia Alexandra Ferreira Santos   +5 more
wiley   +1 more source

Transposase mapping identifies the genomic targets of BAP1 in uveal melanoma [PDF]

, 2018
Table summarizing the RNA-seq results. Differential gene expression results in BAP1-knockdown compared to control OCM-1A cells are shown from the RNA-seq data.
Chen, Xuhua, Cooper, John A, Mitra, Robi D, Onken, Michael D, Qi, Zongtai, Yen, Matthew   +5 more
core   +4 more sources